Free College Football Picks: NCAAF Predictions & Best Bets

Free picks on all NCAAF games for Sept. 20, 2025

West Virginia Mountaineers logo WVU @ Kansas Jayhawks logo KU Sep 20 | 6:00 PM ET
1st Half Spread
Kansas Jayhawks logo KU 1st Half -6.5 (-129)
Best Odds
Pick made: 2 days ago
Mike Spector image
Mike Spector
Author

Kansas has been a fast starter this season, out-scoring opponents by 39 points in the first half. Even in its 42-31 loss to Missouri in its last game, the Jayhawks played to a draw in the first half despite scoring 21 points in the first quarter. The Jayhawks had a week off to correct the things that went wrong in last week’s loss. And since 2022 under head coach Lance Leipold, Kansas has covered five of its six games off a bye. 

 

South Carolina Gamecocks logo SOCAR @ Missouri Tigers logo MIZZ Sep 20 | 7:00 PM ET
Receiving Yards
NH Nyck Harbor u60.5 Receiving Yards (-114)
Best Odds
Pick made: yesterday
Philip Wood image
Philip Wood
Author

Though Harbor is the Gamecocks' leading receiver, he only has seven receptions. The low-volume passing attack will be problematic for him this week against a defense allowing just 100.0 passing yards per game.

Rushing Yards
AH Ahmad Hardy u91.5 Rushing Yards (-102)
Best Odds
Pick made: yesterday
Philip Wood image
Philip Wood
Author

Hardy has rushed for at least 100 yards in all three games this season, but he will struggle this week in his first real test, as he takes on a defense allowing just 3.0 yards per carry.

Score a Touchdown
BN Brett Norfleet Score a Touchdown (Yes: +270)
Best Odds
Pick made: yesterday
Philip Wood image
Philip Wood
Author

Norfleet leads the Tigers with three touchdown receptions, yet his price to score is much higher than other Tigers' receivers. Norfleet can score from anywhere on the field, as shown by his touchdown receptions of one, 11, and 27 yards, and he faces a defense that allowed two passing touchdowns last week.

Rushing Yards
AH Ahmad Hardy o90.5 Rushing Yards (-114)
Best Odds
Pick made: 2 days ago
Rob Paul image
Rob Paul
Publishing Editor

One of the best running backs in the country, dating back to his time at UL Monroe, Ahmad Hardy is coming off a 250-yard rushing performance. Hardy leads the Power Four in rushing yards and has gone for 100-plus in each of his three games at Missouri. South Carolina has a strong defense, but it ranks outside the top 50 in EPA per rush this season. 

Spread
Missouri Tigers logo MIZZ -3.5 (-110)
Best Odds
Pick made: 6 days ago
Rob Paul image
Rob Paul
Publishing Editor

With the uncertainty around LaNorris Sellers, who left last week's loss to Vanderbilt with an injury, Missouri should win handily. The Tigers' offense has thrived behind transfers - QB Beau Pribula, running back Ahmad Hardy, wide receiver Kevin Coleman Jr. - and the defense is right there with it, thanks to Zion Young and Josiah Trotter. Missouri is ranked in the top 25 in SP+ on offense and defense for a reason.

Florida Gators logo FLA @ Miami (FL) Hurricanes logo MIA Sep 20 | 7:30 PM ET
Rushing Yards
MF Mark Fletcher Jr. u75.5 Rushing Yards (-114)
Best Odds
Pick made: 2 days ago
Rob Paul image
Rob Paul
Publishing Editor

Florida's defense isn't the problem this season, and it could create some problems for Miami, especially the Hurricanes' run game. The Gators are No. 3 in the country in EPA per rush on defense and holding opponents to just 3.0 yards per carry. Mark Fletcher Jr. averages only 14 carries per game and was held to 66 rushing yards by the only quality defense he's faced, Notre Dame. 

TD Passes
Carson Beck logo Carson Beck u1.5 TD Passes (+120)
Best Odds
Pick made: 2 days ago
Mike Spector image
Mike Spector
Author

Carson Beck is rising up NFL Draft boards after recording 812 passing yards and total touchdowns, with two of his three games coming against ranked opponents. 

While Beck has the fourth-best QBR among FBS quarterbacks, this is worth a play at plus-money odds against a Florida defense that ranks a respectable seventh in the conference in Passing Plays Success Rate given its tough schedule. 

 

Washington Huskies logo WASH @ Washington State Cougars logo WSU Sep 20 | 7:30 PM ET
Spread
Washington State Cougars logo WSU +21.0 (-112)
Best Odds
Pick made: 23 hours ago
Isaiah Sirois image
Isaiah Sirois
Author

With a massive rivalry game on tap and Washington State hosting, it’s hard to turn down the generous 21 points we can buy at DraftKings. Both the Fremeau Efficiency Index and Sagarin have this game projected within a 14-point margin.

Rushing Yards
Jonah Coleman logo Jonah Coleman u107.5 Rushing Yards (-114)
Best Odds
Pick made: 23 hours ago
Isaiah Sirois image
Isaiah Sirois
Author

Coleman, who followed head coach Jedd Fisch from Arizona to Washington, cleared this line just twice last season and just four times in his career. The Wazzu defense should put up at least some resistance.

Score 2+ Touchdowns
Jonah Coleman logo Jonah Coleman Score 2+ Touchdowns (Yes: +120)
Best Odds
Pick made: yesterday
Rob Paul image
Rob Paul
Publishing Editor

In two games, Washington's Jonah Coleman has seven rushing touchdowns, the most in the country. He's been unstoppable, and a Washington State defense made up of FCS transfers isn't going to stop him. Coleman is the key to an Apple Cup win for the Huskies, with Wazzu ranking No. 96 in EPA per rush on defense this season.

Arizona State Sun Devils logo ASU @ Baylor Bears logo BAY Sep 20 | 7:30 PM ET
Score a Touchdown
Sam Leavitt logo Sam Leavitt Score a Touchdown (Yes: +110)
Best Odds
Pick made: 23 hours ago
Isaiah Sirois image
Isaiah Sirois
Author

Auburn quarterback Jackson Arnold ran for a whopping 137 yards and two scores in Baylor’s home opener, and I wouldn’t be surprised to see Arizona State look to replicate that path to success. Leavitt isn’t the most mobile quarterback, but he can still make plays on the ground. He has 157 rushing yards and three scores to his name already this season. Last year, he tallied 443 rushing yards and five scores. With last year’s star running back, Cam Skattebo, now in the NFL, it makes sense that Leavitt would be getting so more run as, well, a rusher.

Spread
Baylor Bears logo BAY -2.5 (-110)
Best Odds
Pick made: 23 hours ago
Isaiah Sirois image
Isaiah Sirois
Author

How often do quarterbacks start their seasons by throwing for 400-plus yards and three-plus touchdowns in back-to-back games? That’s what Baylor’s Sawyer Robertson did this year, and he now gets to face an Arizona State defense that allowed 279 passing yards (on 8.5 yards per pass attempt) to Mississippi State and Blake Shapen. The Sun Devils rank 58th in yards allowed per pass attempt (6.7). Arizona State head coach Kenny Dillingham got a ton out of this roster last year, but I’m not buying that as a sustainable trend. His quarterback, Sam Leavitt, is down to a 121.8 passing efficiency score this year after posting a 150.2 last season. The spread of 2.5 suggests that this is a pick’em on a neutral site. That gives way too much credit to an Arizona State squad that seems to have regressed year-over-year and clearly misses Cam Skattebo.

Illinois Fighting Illini logo ILL @ Indiana Hoosiers logo IU Sep 20 | 7:30 PM ET
Spread
Indiana Hoosiers logo IU -6.5 (-110)
Best Odds
Pick made: yesterday
Isaiah Sirois image
Isaiah Sirois
Author

Indiana outpaces Illinois in every key metric. The Hoosiers rank 16th in the Fremeau Efficiency Index (FEI) with the 13th-ranked offense and 24th-ranked defense. Illinois clocks in at 27th with the 22nd-ranked offense and the 44th-ranked defense. Indiana quarterback Fernando Mendoza is averaging 9.3 yards per pass attempt and should cook an Illinois defense that allowed 334 passing yards to Duke’s Darian Mensah and ranks 68th in yards surrendered per pass attempt (7.1). Illinois’ signature win, a Week 2 blowout road win over Duke, hinged on some favorable turnover luck and mistakes from the Blue Devils. Cignetti’s team is far more disciplined and won’t give the ball away, which is why his Hoosiers are 11-5 against the spread since last year (and 8-3 as home favorites).

Passing Yards
FM Fernando Mendoza o250.5 Passing Yards (-114)
Best Odds
Pick made: yesterday
Isaiah Sirois image
Isaiah Sirois
Author

The last time this Illinois defense had to stop an opposing quarterback on the road, they let Darian Mensah throw for 334 yards on 9.8 yards per pass attempt. The secondary ranks as a bottom-quartile unit in defensive havoc generated by defensive backs, so don’t expect Mendoza to face much resistance. Illinois should be good enough to hang around against Indiana, forcing them to keep throwing as quarterback Luke Altmyer plays well on the road. Despite facing limited volume, Mendoza is still averaging 236 passing yards per game this year. That’s slightly below this line, but he averaged  273.1 passing yards per game at Cal a year ago, and Indiana’s Kurtis Rourke averaged 253.5 in this offense last year.

Spread
Indiana Hoosiers logo IU -2.5 (-110)
Best Odds
Pick made: 6 days ago
Rob Paul image
Rob Paul
Publishing Editor

These are two fairly evenly matched programs, with both ranking in the top 20 in SP+. I'm backing the Hoosiers to cover thanks to their home-field advantage and their stellar QB play. Transfer Fernando Mendoza has been one of the best passers in the country (79.5 QBR) and should outduel Luke Altmyer in a game that I don't suspect will be full of points.

Wyoming Cowboys logo WYO @ Colorado Buffaloes logo COLO Sep 20 | 10:15 PM ET
Score a Touchdown
SS Sam Scott Score a Touchdown (Yes: +120)
Best Odds
Pick made: 2 days ago
Mike Spector image
Mike Spector
Author

Last week, Houston outgained Colorado 431-300 despite entering the matchup ranked outside the bottom 110 nationally in both Pass and Rush success rate. That is an ominous sign for the Buffaloes going forward, and Cowboys running back Sam Scott should be the biggest beneficiary of a worn down Colorado defense.

 

Spread
Wyoming Cowboys logo WYO +13.5 (-100)
Best Odds
Pick made: 2 days ago
Mike Spector image
Mike Spector
Author

Wyoming’s rushing attack will be the key to staying close this week and keeping the Folsom Field crowd out of the game. Despite Colorado’s secondary being decimated with four key players out for last week’s loss to Houston, the Cougars elected to use their physical advantage up front, and pounded the Buffaloes with 53 rushing attempts. 

 

California Golden Bears logo CAL @ San Diego State Aztecs logo SDSU Sep 20 | 10:30 PM ET
Score a Touchdown
MM Mason Mini Score a Touchdown (Yes: +135)
Best Odds
Pick made: yesterday
Rob Paul image
Rob Paul
Publishing Editor

Cal QB Jaron-Keawe Sagapolutele has been as good as it gets as a freshman. He has six TD passes in two games against FBS teams, with tight end Mason Mini becoming one of his favorite targets. Mini has scored in both games against FBS teams, and San Diego State could struggle to stop him after allowing two touchdowns to Washington State tight end Trey Leckner in its last game

Michigan State Spartans logo MSU @ USC Trojans logo USC Sep 20 | 11:00 PM ET
Score a Touchdown
OK Omari Kelly Score a Touchdown (Yes: +300)
Best Odds
Pick made: 19 hours ago
Philip Wood image
Philip Wood
Author

Though Kelly hasn't scored this season, he is second on the team in receptions and yards. He scored four times last year, and he gets a matchup against a defense allowing 1.7 passing touchdowns per game.

Score a Touchdown
JL Ja'Kobi Lane Score a Touchdown (Yes: -110)
Best Odds
Pick made: 20 hours ago
Philip Wood image
Philip Wood
Author

Lane has scored just once this season, but he found the end zone 12 times last season. I expect a breakout game from him against a defense allowing 2.0 passing touchdowns per game.

Score 2+ Touchdowns
WJ Waymond Jordan Score 2+ Touchdowns (Yes: +225)
Best Odds
Pick made: 20 hours ago
Philip Wood image
Philip Wood
Author

Jordan has scored once in every game this season, and he leads the Trojans in rushing touchdowns. Jordan had eight more carries than any other back last week against Purdue, and he will have plenty of scoring opportunities against a team allowing over 20 points per game to offenses far inferior to USC's.

Passing Yards
JM Jayden Maiava o277.5 Passing Yards (-114)
Best Odds
Pick made: yesterday

Jayden Maiava has passed for 329.6 yards per game this season without dipping below 282 passing yards in any of his three starts. The Michigan State defense was torched through the air by Boston College (390 yards) and also allowed Youngstown State's starting QB to reach 242 yards passing. This feels like a stylstic mismatch that benefits the Trojans.

Total
Michigan State Spartans logo USC Trojans logo o55.0 (-115)
Best Odds
Pick made: yesterday

USC's offense is one of the most explosive in the country, and it does the bulk of its damage through the air. That's where the Trojans can pierce the weak spot of the Michigan State defense to push the scoring pace in this matchup.

I like Sparty, though, coming back with a balanced attack that can contribute to this total after averaging 35.3 points per game to this point.

Score 2+ Touchdowns
WJ Waymond Jordan Score 2+ Touchdowns (Yes: +225)
Best Odds
Pick made: yesterday
Mike Spector image
Mike Spector
Author

Trojans running back Waymond Jordan has been embedded seamlessly into the USC offense, as the JUCO transfer already has a team-leading 286 rushing yards and three rushing touchdowns. Jordan ranks second among Big Ten running backs in yards after contact per rush (5.92), and is a home-run threat averaging 7.3 yards per carry.

USC owns the country’s second-highest scoring offense at 55 points per game, and is projected to score at least five touchdowns based on its team total O/U of 37.5 points. 

 

Receiving Yards
LM Lake McRee o32.5 Receiving Yards (-114)
Best Odds
Pick made: yesterday
Mike Spector image
Mike Spector
Author

USC head coach Lincoln Riley has not only developed three Heisman Trophy-winning quarterbacks in his collegiate career, but has so far guided the Trojans to the top-ranked total offense. USC has averaged 604 yards per game, and while the competition gets stiffer against Michigan State, that is a lot of yards to go around for its talented tight end.

 

Recent News

College football picks & best bets today

Every Saturday - and sometimes Thursday, Friday, and even Monday, Tuesday, Wednesday, or Sunday - there is college football on the schedule, and the Sportsbook Review team shares its top picks and predictions for the biggest games on the board. We cover the betting markets that matter most: spreads, totals, moneylines, and team and player props across all the top matchups in NCAA football.

Our picks widget above highlights our favorite bets each week, with live college football odds pulled from legal sportsbooks. Whether it's a massive SEC showdown or a Group of Five game under the radar, you'll find expert insights and value picks on the games you’re most likely to bet - and watch. Even MACtion.

We go deep into every matchup with predictions on point spreads, Over/Unders, and moneylines, plus popular prop markets like anytime touchdown scorers, QB passing yards, and more. We also mix in parlays and same-game parlays (SGPs) for fans chasing a bigger payout. Our goal is to help you find smart angles to bet - whether you're backing your favorite team or just looking to cash in on a ranked matchup.

Our betting experts lean on advanced metrics like success rate, explosive play percentage, havoc rate, and pace of play. We also study snap counts, injuries, quarterback trends, coaching tendencies, and line movement to help identify sharp plays and the best value across the board.

Bookmark this page and come back all season long for the latest college football picks and betting advice from our experts at Sportsbook Review. You won’t want to be anywhere else come bowl season.

Free college football picks each week

Our college football betting experts have been tracking the futures markets since the final whistle of last season’s national championship game. From the transfer portal and spring practices to coaching changes, preseason polls, and opening odds to win the College Football Playoff, we’ve followed it all.

As the season kicks off and the action heats up, we have you covered every week with breakdowns of the full Saturday slate, the top-25 matchups, and all the key conference showdowns and rivalry games. We’ll monitor how weather could impact games, keep tabs on injury news, and track the betting trends that matter - like why some teams dominate as underdogs or why a certain coach always seems to cover against a rival.

Our expert picks for each game include predictions on who wins outright, the best spread or total play, and player props when and where available. Plus, we’ll bundle our favorite bets into a parlay or same-game parlay (SGP) to give you a shot at a bigger payout. You won’t find gimmicks or guarantees, but our 1-to-5-star confidence ratings show how strongly we feel about each pick, so you know when we’re betting something ourselves.

Make SBR your home for free college football picks from Week 0 through bowl season, the CFP, and the national championship.

Free CFP picks

Once the College Football Playoff picture starts to take shape, our experts ramp up the analysis of every CFP contender. From midseason futures to semifinal previews and national championship breakdowns, we deliver trusted insight into the College Football Playoff odds and sharp picks on the games that matter most.

We evaluate CFP betting markets from every angle - game lines, team totals, and prop bets like first or anytime touchdown scorer. Whether you're betting Michigan vs. Ohio State or a long-shot title future, we have picks based on data, matchups, and line value.

Expect deeper dives as the playoff field is announced and the betting lines tighten. Our goal: find the edge before the market catches up to get you the best value on the college football championship odds.

Free college football moneyline picks

A moneyline bet is as simple as it gets - just pick the winner, no point spread involved. Favorites are listed with a minus sign (‑), and underdogs with a plus (+). You win if your team wins the game, no matter the score.

Example:

TeamMoneyline odds
Ohio State–145
Michigan+125
  • A $100 bet on Ohio State (–145) returns about $69 profit (total payout $169)
  • A $100 bet on Michigan (+125) returns $125 profit (total payout $225)

Moneyline bets are popular when you’re confident a team will win outright, or when you like a live dog to pull off the upset.

Free college football Over/Under picks

Over/Under bets are all about how many total points both teams will combine to score - no need to worry about who wins or by how much.

Books set a number like Over/Under 56.5, and you simply choose:

  • Over if you think the teams will score more than 56.5 combined points
  • Under if you think they’ll score fewer

Odds usually hover around -110, meaning you’d bet $110 to win $100. If the game ends:

  • 31-28 (total 59) → Over wins
  • 24-20 (total 44) → Under wins

The half-point avoids ties (or “pushes”) so your bet always has a clear winner or loser. Many bettors also enjoy Over/Unders for first-half totals, team totals, or even live betting totals based on in-game flow.

Free college football spread picks

Spread betting is the most popular way to bet college football. It levels the playing field between two teams by assigning a point handicap. In lopsided matchups, sportsbooks may not even list a moneyline and you can see spreads of 40 points or larger.

For example:

  • Alabama -14.5 means the Crimson Tide must win by 15 or more to cover the spread
  • Tennessee +14.5 means the Vols can win outright or lose by 14 or fewer to cover

The .5 ensures a win/loss result with no pushes on your picks against the spread. Late in the season, you’ll often see tighter lines and smaller spreads in rivalry games, but early-season matchups can carry big numbers, especially in mismatches between powerhouses and smaller programs.

Free college football prop picks

College football prop bets let you focus on specific moments or player performances rather than the final outcome.

Popular prop bets include:

  • Quarterback passing yards Over/Under
  • Running back rushing yards
  • Anytime touchdown scorer
  • First team to score
  • First-half totals and spreads

For example, you might bet:

  • Arch Manning Over 295.5 passing yards (-115)
  • Jeremiah Smith to score a touchdown (+100)

These bets can offer better value and more entertainment, especially when you’re betting on players you know or games you’re already watching. Props are also great for parlay building and live betting adjustments based on game flow.

You’ll need to use our college football player prop tracker to make sure these props are legal in your state.

How we make our college football picks & predictions

At Sportsbook Review, we’re not just picking based on gut feel or school pride. Every college football prediction is backed by matchup analysis, metrics, and betting trends.

We study:

  • Offensive and defensive efficiency
  • Pace of play and explosive plays
  • Advanced stats like success rate, havoc rate, and red-zone performance
  • Injuries, depth charts, and coaching trends
  • Line movement and sharp action

Our experts monitor every angle, then compare their analysis to the betting odds to find edges and value. Whether you’re betting spreads, totals, or props, we aim to give you actionable picks with real upside.

Why trust our college football experts?

Sportsbook Review has been helping sports bettors for over 20 years. We’ve earned a reputation for honest reviews, sharp picks, and expert analysis that delivers.

Here’s what sets our college football betting team apart:

  • Experience: We’ve been breaking down games and betting lines since the BCS era
  • Specialization: Our experts focus on the conferences and teams they know best - no random guesses here
  • Transparency: We give each pick a 1-to-5-star confidence rating so you know how strongly we feel about it
  • Bet what we believe: Our experts don’t post anything they wouldn’t bet themselves

From September Saturdays to the College Football Playoff, we have you covered. Let us help you find value, win more bets, and enjoy the season.

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