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Notre Dame Fighting Irish running back Jeremiyah Love celebrates after a touchdown against the Georgia Tech Yellow Jackets as we look at our Indiana vs. Notre Dame parlay picks.
Notre Dame Fighting Irish running back Jeremiyah Love celebrates after a touchdown against the Georgia Tech Yellow Jackets. Photo by Brett Davis/Imagn Images.

As the total drops precipitously throughout Friday morning, we’re leaning in on our prediction of a high-scoring contest to kick off the opening round of the College Football Playoff.

Our Indiana vs. Notre Dame parlay picks for CFP Round 1 envisions the Hoosiers leaning on their quarterback to stay in the game against the Irish, who could enjoy another breakthrough from their star running back.

Notre Dame (-6.5) hosts Indiana at Notre Dame Stadium in South Bend, Ind., Friday night at 8 p.m. ET (ABC, ESPN).

Our college football bowl game opt-out tracker has you covered with the latest opt-out news and the impact on the college bowl game odds.

Indiana vs. Notre Dame parlay predictions: College Football Playoff Round 1

College football picks based on the odds from our best college football betting sites.

  • Over 51 (-112) ⭐⭐⭐⭐
  • Jeremiyah Love Over 81.5 rushing yards (-120) ⭐⭐⭐⭐
  • Kurtis Rourke Over 224.5 passing yards (+170) ⭐⭐⭐⭐

Combined odds: +525 via DraftKings | Implied probability: 16.00%

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SGP predictions for Indiana vs. Notre Dame

Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Over 51 (-112) ⭐⭐⭐⭐

We liked the Over on Thursday when it was still up at 52 or 52.5, and we’re not changing our tune Friday now that the number is moving in our favor.

While overlooking the performance of these defenses could be dangerous, I don’t want to ignore the 80.1 combined scoring average for these two offenses. The Irish have not scored fewer than 31 points in a game since mid-September.

DraftKings has lowered the total to 51, while our other best sportsbooks have set it at 51.5. I'm also using this play as part of my college football playoff parlay picks.

Love Over 81.5 rushing yards (-120) ⭐⭐⭐⭐

Although both run defenses in this game have been dominant, Notre Dame hasn’t endured any issues establishing the run against other run defenses that were good on paper. Jeremiyah Love erupted for 130 yards on seven rushing attempts against Army.

Despite rarely being a volume workhorse, Love has cleared this rushing line six times on the season and in each of his last three games. His explosiveness (7.1 yards per carry) allows him to rack up significant totals without insane volume, but he could see an uptick in carries on Friday amid a chilly evening in South Bend. 

The line of Over 81.5 rushing yards at DraftKings is more appealing than the 84.5 at FanDuel.

Our Rob Paul is also backing Love in his Indiana vs. Notre Dame prediction.

Rourke Over 224.5 passing yards (+170) ⭐⭐⭐⭐

Notre Dame boasts one of the top statistical pass defenses in college football this season. But Curt Cignetti and Kurtis Rourke could see blood in the water come Friday after the Fighting Irish allowed a whopping 360 yards through the air to USC in their final regular-season game.

Rourke is no stranger to passing volume after clearing 250 yards seven times this season. We’re taking a more aggressive alternate line for Rourke’s passing yardage to boost our overall parlay odds, with Over 224.5 yards at +170 odds from DraftKings.

A winning $10 wager on this parlay at DraftKings would profit $52.50 as part of your college bowl game predictions.

Elsewhere, Shane Jackson dove in on Rourke too in his Indiana vs. Notre Dame player prop picks.

Indiana vs. Notre Dame expert picks

Indiana vs. Notre Dame live odds

See all of this week's college football odds and NCAAF scores.

Indiana vs. Notre Dame game info

  • When: Friday, Dec. 20
  • Kickoff: 8 p.m. ET
  • Where: Notre Dame Stadium (South Bend, Ind.)
  • How to watch: ABC, ESPN
  • Weather: 28 degrees, 34% chance of precipitation, wind 10-mph N
  • Favorite: Notre Dame -6.5 (-115 via FanDuel)

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