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After explosive offensive performances in Week 1, the Mississippi State Bulldogs and Arizona Wildcats meet for a late-night gathering in Arizona in Week 2. Read on for our Mississippi State-Arizona picks.

Bulldogs head coach Mike Leach’s offense is ready to light the college football world on fire with experienced quarterback Will Rogers running the show again in 2022.

Here are our top picks for Mississippi State-Arizona (odds via FanDuel Sportsbook and DraftKings Sportsbook).

Mississippi State vs. Arizona Picks

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Mississippi State vs. Arizona ATS Pick

Mississippi State -10.5 (-118) ★★★★

Mississippi State’s 84 offensive plays from Week 1 rank 10th in FBS through one week. Rogers was also efficient, completing 38 of 49 attempts for 450 yards and five touchdowns.

Arizona looked good in its opening win over San Diego State, but this is a team that went 1-11 last year while allowing 32.4 points per game (102nd in FBS). Give me the Leach Air Raid in Week 2.

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Mississippi State vs. Arizona O/U Pick

Over 57 (-115) ★★★★

The Bulldogs offense's elite pace means points should be plentiful at Arizona. That’s especially true if Arizona’s troubling defense from last season still struggles to find its footing.

Offensively for the Wildcats, Week 1 offered signs they could contribute meaningfully to this total. Hanging 38 on a San Diego State group that ranked 14th in FBS last year in opponent points per game was a good sign for head coach Jedd Fisch’s offense.

Take the Over at DraftKings instead of FanDuel for a half-point bonus on the line.

Mississippi State vs. Arizona Prop Pick

Rogers Over 368.5 passing yards (-114) ★★★

Will Roger's efficiency — 450 yards and 77.5% completion mark — make him a candidate for gaudy numbers on a weekly basis.

Though Rogers averaged a few yards below the 368.5 required for this prop last season, he beat this passing mark in each of his five road games. In those contests, Rogers averaged 408.6 passing yards.

Where to Bet on Mississippi State vs. Arizona Picks

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Mississippi State-Arizona picks made 9/9/2022 at 1:47 p.m. ET