College Football Week 15 Predictions: Picks & Odds for Every Championship Game

The regular season is wrapped, and nine title games will be played on Friday and Saturday before the final College Football Playoff rankings are released as we make our college football conference championship predictions.
- Led by Heisman Trophy odds contender Ashton Jeanty, Boise State toppled UNLV in the Mountain West Championship to solidify its spot as the G5 College Football Playoff pick
- With both Georgia and Texas' College Football Playoff odds being pulled as borderline CFP locks, they'll be playing for a first-round bye in the SEC Championship
- Oregon is the No. 1 team in the country and leads the college football championship odds as the Ducks get set to play Penn State in the Big Ten Championship
With three conference championships on Friday and six more on Saturday, there are several AP Top 25 set to take the field with College Football Playoff seeding on the line during conference championship weekend.
College football picks & predictions for every conference championship
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- Marshall vs. Louisiana prediction: Sun Belt Championship
- Penn State vs. Oregon championship early picks
- Penn State vs. Oregon prediction: Big Ten Championship
- Penn State vs. Oregon player props: Big Ten Championship
- Clemson vs. SMU championship early picks
Don't miss the rest of our conference championship college football picks.
College football odds for Saturday
College football odds via DraftKings and subject to change. Follow the latest college football scores for line history and matchup info.
Marshall vs. Louisiana odds: Sun Belt Championship
Prediction: Marshall +5.5 (-105 via Caesars) ⭐⭐⭐⭐
Pick made by Gabe Henderson.
- When: Saturday, Dec. 7 (7:30 p.m. ET)
- Where: Cajun Field (Lafayette, La.)
- How to watch: ESPN
- Moneyline: Marshall (+164) | Lousiana (-198)
- Spread: Marshall +5.5 (-110) | Louisiana -5.5 (-110)
- Total: 56.5 (-110/-110)
Penn State vs. Oregon odds: Big Ten Championship

Prediction: Jordan James Under 95.5 rushing yards (-114 via FanDuel) ⭐⭐⭐⭐
Pick made by Phil Wood.
- When: Saturday, Dec. 7 (8 p.m. ET)
- Where: Lucas Oil Stadium (Indianapolis)
- How to watch: CBS
- Moneyline: Penn State (+142) | Oregon (-170)
- Spread: Penn State +3.5 (-110) | Orgon -3.5 (-110)
- Total: 49.5 (-110/-110)
Clemson vs. SMU odds: ACC Championship
Prediction: Cade Klubnik Over 247.5 passing yards (-115 via BetMGM) ⭐⭐⭐⭐⭐
Pick made by Brenden Schaeffer.
- When: Saturday, Dec. 7 (8 p.m. ET)
- Where: Bank of America Stadium (Charlotte)
- How to watch: ABC
- Moneyline: Clemson (+114) | SMU (-135)
- Spread: Clemson +2.5 (-112) | SMU -2.5 (-108)
- Total: 55.5 (-108/-112)
College football picks roundup: Conference championships
- College football conference championship ATS picks
- College football conference championship upset picks
- College football conference championship player props
- College football conference championship best bets
- College football conference championship expert picks
- College football touchdown scorer predictions
- College football player props for Saturday
- College football best bets for Saturday
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