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Oregon defensive lineman Derrick Harmon celebrates a sack against Washington. We're making our college football conference championship predictions for all nine games.
Oregon defensive lineman Derrick Harmon celebrates a sack against Washington. Photo by Ben Lonergan/The Register-Guard/USA TODAY NETWORK via Imagn Images.

The regular season is wrapped, and nine title games will be played on Friday and Saturday before the final College Football Playoff rankings are released as we make our college football conference championship predictions.

  • Led by Heisman Trophy odds contender Ashton Jeanty, Boise State toppled UNLV in the Mountain West Championship to solidify its spot as the G5 College Football Playoff pick
  • With both Georgia and Texas' College Football Playoff odds being pulled as borderline CFP locks, they'll be playing for a first-round bye in the SEC Championship
  • Oregon is the No. 1 team in the country and leads the college football championship odds as the Ducks get set to play Penn State in the Big Ten Championship

With three conference championships on Friday and six more on Saturday, there are several AP Top 25 set to take the field with College Football Playoff seeding on the line during conference championship weekend. 

College football picks & predictions for every conference championship

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Don't miss the rest of our conference championship college football picks.

College football odds for Saturday

College football odds via DraftKings and subject to change. Follow the latest college football scores for line history and matchup info.

Marshall vs. Louisiana odds: Sun Belt Championship

Prediction: Marshall +5.5 (-105 via Caesars) ⭐⭐⭐⭐  

Pick made by Gabe Henderson.

  • When: Saturday, Dec. 7 (7:30 p.m. ET)
  • Where: Cajun Field (Lafayette, La.)
  • How to watch: ESPN
  • Moneyline: Marshall (+164) | Lousiana (-198)
  • Spread: Marshall +5.5 (-110) | Louisiana -5.5 (-110)
  • Total: 56.5 (-110/-110)

Penn State vs. Oregon odds: Big Ten Championship

Penn State defensive end Abdul Carter pressures Maryland quarterback MJ Morris. We cover the Big Ten title game as part of our college football conference championship predictions.
Penn State defensive end Abdul Carter pressures Maryland quarterback MJ Morris. Photo by Matthew O'Haren via Imagn Images.

Prediction: Jordan James Under 95.5 rushing yards (-114 via FanDuel) ⭐⭐⭐⭐

Pick made by Phil Wood.

  • When: Saturday, Dec. 7 (8 p.m. ET)
  • Where: Lucas Oil Stadium (Indianapolis)
  • How to watch: CBS
  • Moneyline: Penn State (+142) | Oregon (-170)
  • Spread: Penn State +3.5 (-110) | Orgon -3.5 (-110)
  • Total: 49.5 (-110/-110)

Clemson vs. SMU odds: ACC Championship

Prediction: Cade Klubnik Over 247.5 passing yards (-115 via BetMGM) ⭐⭐⭐⭐⭐

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Pick made by Brenden Schaeffer.

  • When: Saturday, Dec. 7 (8 p.m. ET)
  • Where: Bank of America Stadium (Charlotte)
  • How to watch: ABC
  • Moneyline: Clemson (+114) | SMU (-135)
  • Spread: Clemson +2.5 (-112) | SMU -2.5 (-108)
  • Total: 55.5 (-108/-112)

College football picks roundup: Conference championships

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