College Football Expert Picks Week 4: Top CFB Predictions This Week
The Week 4 slate has a few games that could shake up the college football championship odds, and in our college football expert picks we highlight some of the must-watch matchups.
- The winner of USC vs. Michigan will jump up the College Football Playoff odds
- LSU is a 24.5-point favorite against UCLA at our college football betting sites as the Tigers look to bounce back after a sloppy Week 3 outing
- Travis Hunter has the opportunity to continue rising up the Heisman Trophy odds with Colorado set to begin Big 12 play against Baylor
As part of our Week 4 college football predictions, we're making our expert picks for some of the top games on the schedule this week.
Don't miss Shane Jackson's college football player props or Mike Spector's college football predictions and best bets for more action.
College football expert picks for Week 4
College football odds as of Thursday and subject to change. See all of our college football picks for more on this week's top matchups.
| Rob Paul | C Jackson Cowart | |
|---|---|---|
| Marshall vs. Ohio State | Quinshon Judkins Over 74.5 rushing yards (-114 via FanDuel) | Ohio State Over 45.5 points (-115 via DraftKings) |
| USC vs. Michigan | Lake McRee 40+ receiving yards (+125 via DraftKings) | USC -5 (-112 via DraftKings) |
| UCLA vs. LSU | Garrett Nussmeier Over 294.5 passing yards (-114 via FanDuel) | LSU Over 38.5 points (-120 via DraftKings) |
| Miami (OH) vs. Notre Dame | Riley Leonard anytime TD scorer (-138 via bet365) | Miami (OH) +28 (-110 via BetMGM) |
| Vanderbilt vs. Missouri | Luther Burden Over 77.5 receiving yards (-115 via Caesars) | Over 52.5 (-110 via FanDuel) |
| Baylor vs. Colorado | Travis Hunter Over 90.5 receiving yards (-114 via FanDuel) | Baylor +2 (-110 via Caesars) |
Top picks for Week 4
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Marshall vs. Ohio State prediction: Quinshon Judkins Over 74.5 rushing yards ⭐⭐⭐⭐
Marshall's defense is 91st in SP+ and 83rd in EPA per rush. It allowed 208 rushing yards to Virginia Tech in its last outing.
Quinshon Judkins is excelling in Chip Kelly's scheme and has forced 12 missed tackles in just two games, per PFF. He leads Ohio State in carries (22) and rushing yards (163), and if he surpasses this number, a $10 bet pays an $8.77 profit.
Best odds: -114 via FanDuel | Implied probability: 53.27%
New customers only. Deposit min. $5. Place first bet of $5+ and win $150 in Bonus Bets (within 72 hours).
USC vs. Michigan prediction: USC -5 ⭐⭐⭐⭐
Look, I know this line has moved by nearly two touchdowns in the span of a few weeks. But the market moved aggressively against Michigan two weeks ago, and Texas rewarded bettors with a blowout win.
The Wolverines' offense is disjointed right now, and I don't expect that to suddenly change with Alex Orji - who has seven career pass attempts - making his first-ever start against this vastly improved USC defense under D'Anton Lynn.
Best odds: -112 via DraftKings | Implied probability: 52.83%
Terms and conditions apply.
–– C Jackson Cowart (SBR | Twitter/X)
USC vs. Michigan prediction: Lake McRee 40+ receiving yards ⭐⭐⭐⭐
Miller Moss' favorite target is clearly Lake McRee. He leads USC in receiving yards (137) and ranks 10th among Power 4 tight ends in yards per route run (2.83).
Michigan's defense is worse against the pass (40th in EPA per dropback) than the run (23rd in EPA per rush). That opens the door for McRee to go over 40 receiving yards for the third straight game, and it would turn a $10 bet into a $12.50 profit with our DraftKings promo code.
Best odds: +125 via DraftKings | Implied probability: 44.44%
Our Shane Jackson dives deeper into this matchup with his USC vs. Michigan prediction.
UCLA vs. LSU prediction: LSU Over 38.5 points ⭐⭐⭐⭐
After losing Lynn to their crosstown rivals before the season, the Bruins promptly gave up 42 points last week to Indiana - tied for the Hoosiers' third-most against a Big Ten opponent since the Nate Sudfeld era (2012-15).
Now UCLA will face an LSU offense led by an NFL-caliber quarterback in Garrett Nussmeier, who led the Tigers to 36 points last week against a superior South Carolina defense.
Mike Spector also expects LSU to roll in his UCLA vs. LSU prediction.
Best odds: -120 via DraftKings | Implied probability: 54.55%
Terms and conditions apply.
–– C Jackson Cowart (SBR | Twitter/X)
Vanderbilt vs. Missouri prediction: Luther Burden Over 77.5 receiving yards ⭐⭐⭐⭐
Vanderbilt's defense is brutal. It's 96th in SP+ and 90th in EPA per dropback after allowing Georgia State to throw for 269 yards last week.
The Commodores won't be able to stop Luther Burden. He's one of the best players in the country and is averaging 9.6 yards after the catch. Burden went for 140 yards against Vandy last year, if he does it again a $10 bet pays an $8.70 profit.
Best odds: -115 via Caesars | Implied probability: 53.49%
New users only. Register using eligible promo code. First bet to settle must lose to qualify. Max. Bonus Bet: $1K. Expires in 14 days. Void where prohibited. Full terms.
Baylor vs. Colorado prediction: Baylor +2 ⭐⭐⭐⭐
Is it still in vogue to fade Colorado? The Buffaloes silenced the skeptics last week with a 28-9 win over rival Colorado State, but they'll face a stiffer test against Baylor, which is fresh off dismantling Air Force in a 31-3 home rout.
The Bears' defense quietly ranks second in opponent success rate. While the competition hasn't been the best, I still think Baylor deserves more respect in the betting market - which always tends to be the case for Colorado's opponent.
Mike Spector likes the Bears as underdogs for his Baylor vs. Colorado prediction.
Best odds: -110 via Caesars | Implied probability: 52.38%
New users only. Register using eligible promo code. First bet to settle must lose to qualify. Max. Bonus Bet: $1K. Expires in 14 days. Void where prohibited. Full terms.
–– C Jackson Cowart (SBR | Twitter/X)
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