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Indiana quarterback Kurtis Rourke throws a pass against Maryland. We're backing the Hoosiers in our college football Week 8 picks against the spread.
Indiana quarterback Kurtis Rourke throws a pass against Maryland. Photo by Robert Goddin via Imagn Images.

With another loaded slate, our college football Week 8 picks against the spread focus on three surging programs.

There are some massive matchups on Saturday and our Week 8 college football predictions look at the most important games this weekend.

College football ATS picks Week 8: Marquee games

College football picks via DraftKings and subject to change; pick confidence based on a 1-to-5-star scale.

MatchupPickConfidence
Boston College vs. Virginia TechVirginia Tech (-6.5)⭐⭐⭐
Oregon vs. PurdueOregon (-27) ⭐⭐⭐
Oklahoma State vs. BYUBYU (-9.5)⭐⭐⭐
Miami vs. LouisvilleMiami (-4.5)⭐⭐⭐⭐
Virginia vs. ClemsonVirginia (+21)⭐⭐⭐
Nebraska vs. IndianaIndiana (-6.5)⭐⭐⭐⭐
Auburn vs. MissouriMissouri (-4.5)⭐⭐⭐
East Carolina vs. ArmyArmy (-15)⭐⭐⭐⭐
Alabama vs. TennesseeAlabama (-3)⭐⭐⭐
Notre Dame vs. Georgia TechNotre Dame (-12)⭐⭐⭐
Michigan vs. IllinoisMichigan (-3.5)⭐⭐⭐
Colorado vs. ArizonaColorado (+4)⭐⭐⭐⭐
Baylor vs. Texas TechTexas Tech (-6.5)⭐⭐⭐
USC vs. MarylandUSC (-7.5)⭐⭐⭐
LSU vs. ArkansasLSU (-3)⭐⭐⭐⭐
Georgia vs. TexasTexas (-4)⭐⭐⭐⭐
Kansas State vs. West VirginiaKansas State (-3)⭐⭐⭐⭐
Iowa vs. Michigan StateIowa (-6)⭐⭐⭐
Kentucky vs. FloridaFlorida (+1)⭐⭐⭐
TCU vs. UtahUtah (-4.5)⭐⭐⭐
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My favorite ATS picks this week

College football picks as of Tuesday. Our NEW college football player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

Nebraska vs. Indiana (-6.5)

Best odds: -110 via FanDuel | Implied probability: 52.38%

Nebraska was supposed to be the team to break through in the Big Ten this season, instead, it's been Indiana thanks to new head coach Curt Cignetti bringing in so many quality transfers.

Chief among them is Rourke, who has the Hoosiers offense ranked second in the country in EPA per dropback. He should be able to score enough against a Cornhuskers defense outside of the top 30 in EPA per dropback.

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The real difference though will be Indiana's defense against Nebraska's offense. The Cornhuskers are just 83rd in SP+ on offense while Indiana's front seven has it ranked 30th in SP+ on defense.

If the Hoosiers cover for the sixth straight game, a $10 bet pays a $9.09 profit.

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East Carolina vs. Army (-15.5)

Best odds: -108 via DraftKings | Implied probability: 51.92%

Only two teams are a perfect 6-0 ATS this season, BYU and Army. The Black Knights are ranked in the AP Top 25 and have won every game this season by at least 17 points.

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Nobody in the AAC can seem to stop the triple option with Army leading the country in rushing yards per game (369.8) and ranked first in EPA per dropback. Meanwhile, East Carolina's defense just allowed 55 points to a bad Charlotte team.

And the Pirates' offense is even worse, ranked 114th in SP+ outside of the top 90 in both EPA per rush and dropback. The Black Knights' defense is allowing the 10th-fewest yards per game (267.3).

Another cover for Army would pay a $9.26 profit on a $10 bet.

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LSU (-3) vs. Arkansas 

Best odds: -105 via BetMGM | Implied probability: 51.22%

After losing to USC to open the season and failing to cover in its first four games of the year, LSU seems to have gotten it together. The Tigers have covered in their last two, including winning outright as a 4-point dog against Ole Miss.

Arkansas is coming off a bye after beating Tennessee, but QB Taylen Green is dealing with a knee injury that knocked him out of the upset. Without him 100% against LSU, the Razorbacks will struggle to move the ball with their offense just 71st in EPA per dropback.

And they'll likely need to score to cover with LSU's explosive attack ranked fifth in SP+ and 14th in EPA per dropback. QB Garrett Nussmeier has been on a tear with six big-time throws in two SEC games, per PFF.

If Nussmeier can lead another high-scoring win and cover, a $10 bet on the Tigers pays a $9.52 profit.

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College football betting odds pages

Here are our best college football betting sites:

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