Arkansas vs. LSU Prediction, Picks & Odds Today: College World Series Preview & Best Bets

Can LSU beat Arkansas again in the College World Series and send the Razorbacks home?

Rob Paul

Last Updated: June 18, 2025 4:47 PM EDT • 4 minute read

Two powerhouses collide at 7 p.m. ET (ESPN) tonight in Omaha as the third-ranked Arkansas Razorbacks (50-14) face off against the sixth-ranked LSU Tigers (50-15) with a chance to reach the College World Series Finals.

Our Arkansas vs LSU prediction and odds are targeting the Tigers, despite the Razorbacks being -125 favorites based on the best College World Series odds from our baseball betting sites.

🔮 Arkansas vs LSU prediction & picks

Arkansas' elite pitching has carried it to the College World Series semifinal, with Gage Wood's 19-strikeout no-hitter in an elimination game among the best college pitching performances of all time.

However, you won't be seeing him at all tonight, and that might ultimately end the season of this talented Razorbacks team. While Arkansas took down Murray State 3-0 behind Wood's pitching and then blew by UCLA 7-3 on Tuesday, the Razorbacks opened the College World Series by dropping a game to LSU 4-1.

Can Arkansas get revenge tonight at Charles Schwab Field without two of its top pitchers available? Or will the Tigers pull out another W with their ace expected to be on the mound?

🆚 Who will win Arkansas vs LSU?

Anthony Eyanson (11-2, 2.92 ERA) will likely be on the mound to start tonight after he threw just 45 pitches in three innings in the rain-delayed win over the Bruins on Monday. That gives LSU a major edge over Arkansas. The Razorbacks can't go to Wood or Zach Root, which makes projecting their starting pitcher a little tricky, and they could rely on a platoon of pitchers.

Given Eyanson's success this season, particularly against Arkansas earlier this year when he pitched six shutout innings and struck out 11, LSU has the edge going into this matchup, even as the underdog. The Tigers have beaten the Razorbacks in three of four games this year, outscoring them 26-15 in the process.

Not only does LSU have the better pitching situation in a stadium known as a pitcher's park, the Tigers also have some big swinging bats. Derek Curiel, Jared Jones, Ethan Frey, and Daniel Dickinson should be able to do enough offensively to win this game.

✅ Moneyline pick: LSU ⭐⭐⭐⭐
📊 Best odds: -106 via FanDuel ($10 to win $9.43)

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🎯 Exact score prediction: LSU 4, Arkansas 2

Although this should be a tight game thanks to the pitching of Eyanson, and Arkansas' depth at the position, LSU's lineup is bound to pop off at some point. Jones is a mashing monster with 21 dingers to his name and a .325/.420/.619 slash line, and he's surrounded by support in the lineup. Curiel and Frey are both batting better than .330 and both have an OPS over 1.000.

Even if Arkansas' can start one of Gabe Gaeckle or Landon Beidelschies, with its strong bullpen, LSU just has too much pop in its bats to stay quiet for long. Expect this one to be low-scoring late into the game.

📊 Best odds: +4500 via DraftKings ($10 to win $45)

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📊 Arkansas vs LSU betting odds

Here are the latest Arkansas vs LSU odds courtesy of ESPN BET as of Wednesday morning.

💰 Moneyline

Arkansas: -125
LSU: -110

💰 Run line

Arkansas: -1.5 (+120)
LSU: +1.5 (-165)

💰 Over/Under

Over 10.5 (-130)
Under 10.5 (-105)

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📺 How to watch Arkansas vs LSU tonight

📅 Date: Wednesday, June 18
🕒 Start time: 7 p.m. ET
📍 Location: Charles Schwab Field (Omaha, Neb.)
📺 TV: ESPN

💵 Best college baseball betting sites

Want to bet on Arkansas vs. LSU? Check out the best baseball betting sites and best sportsbook promos for today's College World Series games:

FanDuel Promo Code | Read our FanDuel Review
DraftKings Promo Code | Read our DraftKings Review
Hard Rock Bet Promo Code | Read our Hard Rock Bet Review

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Written by:
Rob Paul

Rob is a Publishing Editor at Sportsbook Review. He’s been with the team since early 2024, with this being his first full-time role in the sports betting industry. Before joining SportsbookReview.com, he contributed to various sports outlets, including FanSided and Pro Football Network. During that period, he spent five years working full-time as a local community journalist, after attending Durham College for journalism and Wilfrid Laurier University for history. He previously hosted an NFL draft and college football-focused podcast where he had the opportunity to interact with future NFL players such as Maxx Crosby and Quinn Meinerz. Rob has spent multiple years working as a freelance podcast producer for numerous sports-related podcasts while making guest appearances on several college football shows. He’s also made guest appearances on SportsTalk Mississippi on several occasions to talk all things NFL draft. Rob values the way sports betting acts as a catalyst for telling stories and growing interest in certain sports, particularly FCS football, WNBA, and mid-major college basketball. He’s always been drawn to the more obscure teams and conferences in major college sports, but most of all, Rob loves using stats to find the best player props to back.