Best Home Run Predictions Tonight: MLB Odds, Picks & Prop Bets for May 30

We have four tasty home run picks for Friday night's action, featuring the biggest name in baseball in a potential World Series preview.

Andrew Brennan

Last Updated: May 30, 2025 3:27 PM EDT • 3 minute read

Home Run Predictions Tonight: Best MLB Odds, Picks & Prop Bets for May 30 — Pictured: Los Angeles Dodgers designated hitter Shohei Ohtani is congratulated in the dugout after hitting a three-run home run against the Athletics. Photo by Jayne Kamin-Oncea via Imagn Images.

How could we offer our best home run predictions tonight without featuring one of the stars headlining our Yankees vs. Dodgers prediction. So we went with the $700-million man, Shohei Ohtani.

He joins three other sluggers in our home run parlay, which pays out nearly $3,200 in profit if it hits!

💰 MLB best home run predictions & odds tonight: May 30

Here are my best home run predictions and odds tonight, with my pick confidence based on a 1-to-5-star scale. You can also check out our MLB player prop odds tool for the latest MLB odds at the best legal sportsbooks in your region.

🧨 Marcell Ozuna to hit a home run (+400 via ESPN BET) vs. Red Sox ⭐⭐⭐⭐
🧨 Ketel Marte to hit a home run (+450 via bet365) vs. Nationals ⭐⭐⭐
🧨 Jorge Polanco to hit a home run (+480 via FanDuel) vs. Twins ⭐⭐⭐⭐
🧨 Shohei Ohtani to hit a home run (+310 via BetMGM) vs. Yankees ⭐⭐⭐⭐

🚀 Best home run parlay picks

Here is our best MLB home run parlay for Friday's baseball action; use our parlay calculator to get the best odds for any parlay.

💣 Marcell Ozuna to hit a home run (+350)
💣 Ketel Marte to hit a home run (+260)
💣 Jorge Polanco to hit a home run (+480)
💣 Shohei Ohtani to hit a home run (+240)

Parlay odds: +31846 via FanDuel ($10 to win $3,184.60)

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💣 Best home run prediction tonight: MLB expert picks & prop bets

Here's a breakdown of my best home run prop prediction tonight. Check out the rest of our MLB picks along with our guide on how to bet on MLB.

⚾ Shohei Ohtani (Dodgers) to hit a home run ⭐⭐⭐⭐

Best odds: +310 via BetMGM (bet $10 to win $31)

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It seems our best sports betting sites are pricing Ohtani's hitting Overs at relatively long odds with his Dodgers squaring off against Cy Young odds contender Max Fried. Let me be clear: I don't care who Ohtani is facing. If you're going to give me these odds on him to hit a home run - or the +110 price I bet on for him to go Over 1.5 total bases - I'm firing off a bet.

We're talking about the league leader in home runs. We're talking about a man whose Statcast page is more red than Cody Bellinger's eyes will be at first pitch tonight. We're talking about the GOAT.

So, sure, Fried is very good and induces a ton of ground balls. But he's not immune to giving up a long ball or two, and his 1.29 ERA is going to regress eventually. I'm not sure there's a better spot to pick on him to struggle than tonight against Ohtani and Co.

📊 Yankees vs. Dodgers odds

💵 Best MLB betting sites

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Written by:
Andrew Brennan

Andrew Brennan is a publishing editor for Sportsbook Review. He also heads the website’s MLB coverage, from the various futures markets to daily picks. Andrew believes a math-based approach is the best way to enjoy long-term success in sports betting, and he’s spent the better part of the last year fine-tuning his own process for MLB, NBA, and NFL picks. Andrew uses eight different sportsbooks to find the best odds available and various projection models to gather as much information as he can. His most used sportsbooks are bet365, FanDuel, and theScore Bet. When it comes to daily projection models, he regularly references NumberFire across all sports, as it’s one of the best free tools available. In terms of which daily markets Andrew attacks, he almost exclusively bets on pitcher strikeouts for baseball. When the winter rolls around, you’ll see him providing more variety when it comes to the NBA (points, assists, rebounds) and NFL (almost any offensive-based player prop). He used these tools to go +150 units in 2023. Andrew is also a passionate fantasy sports player. He’s played fantasy football, fantasy Premier League, and fantasy baseball for the last decade. He graduated from Durham College with his diploma in journalism after earning his degree in law from Carleton University. He’s worked in sports media since early 2017, first contributing at FanSided before moving to theScore. He joined SBR in 2022.