Cubs vs. Yankees Prediction, Odds & Best Bets: Will New York Win Its Sixth Straight?

The New York Yankees (53-41) dominated the Chicago Cubs (55-39) in yesterday’s series opener, and our Cubs vs. Yankees prediction examines whether or not the Bronx Bombers can win their sixth straight game for the first time all season. New York is a -160 moneyline betting favorite at our best sports betting sites ahead of first pitch from Yankee Stadium at 1:05 p.m. ET (MLBN).

The Cubs and Yankees each have southpaws that lead the team in wins toeing the rubber, Matthew Boyd and Max Fried, and each plays a key role in our Cubs vs. Yankees best bets.

• Cubs vs. Yankees prediction: Yankees to win (-160 via bet365) ⭐⭐⭐⭐⭐
• Best Cubs vs. Yankees player props: Jazz Chisholm Jr. Under 0.5 hits (+110 via DraftKings) ⭐⭐⭐⭐

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✅ Cubs vs. Yankees prediction: Yankees to win (-160 via bet365)

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The Yankees have won five straight games for the third time this season, and our Cubs vs. Yankees prediction expects New York to secure its first six-game winning streak with Fried on the mound. 

There is something special happening in the Bronx this week, as the Yankees entered yesterday’s series opener off a historic win. On Thursday, the Yankees beat the Mariners after being no-hit into the eighth inning and trailing by five runs, making them the first team to win a game like that since 1977. It was also New York’s first win when trailing by five-plus runs in the eighth inning or later since June 2016.

The Yankees entered the series slugging .539 during their four-game winning streak, while batting .394 with runners in scoring position. They improved upon those numbers yesterday, going 6-for-13 with runners in scoring position. New York also had seven extra-base hits, including three home runs from Cody Bellinger, who ran his hitting streak to 16 games. 

Chicago has won its last 11 day games following a road loss, but I am still making a New York victory my Cubs vs. Yankees best bet. I would not put anyone off laying the -1.5 runs at +135 odds for the best return, but a $6.25 profit on a winning $10 moneyline wager through bet365’s -160 odds is still good value, so take advantage of a bet365 bonus code.

💰 Best Cubs vs. Yankees player props

✅ Best Cubs vs. Yankees player prop: Jazz Chisholm Jr. Under 0.5 hits (+110 via DraftKings)

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Chisholm Jr. enters amid an eight-game hitting streak, during which he has raised his batting average to .252 for the first time since early April. However, Boyd has been tough on left-handed batters with three extra-base hits allowed and a .223/.291/.255 slash line in 94 at-bats, which has us backing this Under as our best Cubs vs. Yankees player prop.  

This line is still inflated because of how hot Chisholm has been since returning from the IL. In the 30 games prior to his IL stint, he batted .181 with seven home runs, a .304 on-base percentage, a .410 slugging percentage, and a 102 wRC+. In the 33 games since his return, he is slashing .314/.391/.620 with 10 home runs.

I expect Boyd and the Cubs bullpen to slam the door on Chisholm’s hitting streak. Among the best sports betting apps where one can back the Under on hits, you can get the best value at +110 odds by using a DraftKings promo code.

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❓MLB betting FAQs

How do betting odds work?

Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common. 

What is the run line in baseball?

The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.

What does moneyline mean in betting?

The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet—just pick the winner.

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