Dodgers vs. Giants Prediction, Odds & Best Bets: Will Los Angeles Snap Seven-Game Skid?

The Los Angeles Dodgers (56-39) are amid their longest losing streak since 2017, and they look to avoid another series loss to the rival San Francisco Giants (52-43) as we dive into our Dodgers vs. Giants prediction.

Oddsmakers have faith in Los Angeles ending its seven-game losing streak, as it is a -140 moneyline betting favorite at our best sports betting sites. With Shohei Ohtani on the mound a day after blasting a ball into McCovey Cove, our Dodgers vs. Giants best bets focus on a different slugger’s batter prop.

First pitch from Oracle Park in San Francisco is set for 4:05 p.m. ET.

• Dodgers vs. Giants prediction: Dodgers to win (-140 via bet365) ⭐⭐⭐⭐
• Best Dodgers vs. Giants player props: Willy Adames to record 2+ total bases (+170 via DraftKings) ⭐⭐⭐⭐

⚾ Dodgers vs. Giants prediction & odds

🔎 Our NEW MLB player prop odds tool can help you find the best MLB odds to make your best MLB picks.

📊 Live Dodgers vs. Giants odds

💰 Dodgers vs. Giants prediction & best bet

✅ Dodgers vs. Giants prediction: Dodgers to win (-140 via bet365)

Bet $5, Get $150 in Bonus Bets Win or Lose*

*Deposit required. Mobile app only. Bonus Bets wager excluded from returns. T&Cs, time limits and exclusions apply. Gambling problem? Call 1-800-GAMBLER

Claim Now

Prior to last night’s loss in the series opener, Los Angeles had a minus-34 run differential during its six-game losing streak, following a plus-100 run differential in its first 88 games. But it showed grit in last night’s 8-7 loss, which is why I am making a four-star play on its moneyline odds as my Dodgers vs. Giants prediction.

Shohei Ohtani had batted .150 in the 11 games leading up to yesterday’s series opener. And while he had 13 strikeouts in that span, he still connected for two home runs, with a third coming yesterday. He was a big reason the Dodgers scored seven runs yesterday after scoring 10 combined runs in the six-game losing streak. 

Had Los Angeles faded into the night after trailing 8-2 yesterday, I would be staying far away from it as today’s Dodgers vs. Giants best bet. But the Dodgers gave themselves something to feed off of, clawing back to 8-7, and putting two runners on base in the ninth inning. 

Los Angeles has as high as a 60.63% implied probability through Caesars’ and DraftKings’ -154 moneyline odds, so there is great value in the -140 at bet365. I am backing the Dodgers to win their 10th straight day game against a divisional opponent when coming off a loss.

💰 Best Dodgers vs. Giants player props

✅ Best Dodgers vs. Giants player prop: Willy Adames to record 2+ total bases (+170 via DraftKings)

Bet $5, Get $150 + $1K Deposit Bonus

Terms and conditions apply.

Claim $150

Given how hot Adames has been, it was surprising to see his O/U for total bases set at 0.5 (the Over was juiced to -140). I was always going to make the Over of 1.5 my best Dodgers vs. Giants player prop, and now I am thrilled to get +170 odds on his alternate total bases line.

Adames entered yesterday’s series opener slugging .520 in his previous 28 games. In that span, he belted six homers and drove in 19 runs while totaling a .900 OPS, a far cry from his .303 slugging percentage through the first 65 games. Given that he followed up with a home run and triple in last night’s win, I love his chances for an extra-base hit or multi-hit game today.

💡 More MLB predictions today

• MLB home run predictions
• Cubs vs. Yankees prediction
• Dodgers vs. Giants prediction
• Rangers vs. Astros prediction
• Phillies vs. Padres prediction

❓MLB betting FAQs

How do betting odds work?

Betting odds represent the probability of a specific outcome and determine how much money you can win on a bet. There are three main formats: American odds, Decimal odds, and Fractional odds. In the U.S., American odds are most common. 

What is the run line in baseball?

The run line in baseball is a form of point spread betting unique to MLB. It typically sets a standard spread of 1.5 runs, meaning the favored team must win by at least two runs to cover the run line, while the underdog can lose by one run or win outright to cover.

What does moneyline mean in betting?

The moneyline in betting refers to a wager on which team or player will win the game outright, with no point spread involved. It’s the most straightforward type of sports bet—just pick the winner.

💵 Best MLB betting sites

Want to bet on Dodgers vs. Giants? Check out the best MLB betting sites and best sportsbook promos for today's MLB games:

• FanDuel Promo Code | Read our FanDuel Review
• DraftKings Promo Code | Read our DraftKings Review
• Hard Rock Bet Promo Code | Read our Hard Rock Bet Review

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.