Shohei Ohtani Player Prop Picks: Best Bets For MVP's 2025 Pitching Debut

Yes, you heard it right - he's back.

We've got our best Shohei Ohtani prop picks to drop as the NL MVP odds favorite returns to the mound for the first time since 2023. Is he on a pitch count? What are the Padres' numbers against him? We answer all of these questions below.

💰 Best Shohei Ohtani prop picks for Padres vs. Dodgers

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✅ Shohei Ohtani prop bet: Over 1.5 strikeouts (+110 via Caesars) ⭐⭐⭐⭐⭐
✅ Shohei Ohtani prop bet: Over 1.5 bases (-105 at BetMGM) ⭐⭐⭐⭐
✅ Shohei Ohtani prop bet: Over 0.5 RBI (+130 at Caesars) ⭐⭐⭐⭐ 

📊 Parlay odds: +843 via Caesars ($10 pays $84)

🔥 Shohei Ohtani Over 1.5 strikeouts ⭐⭐⭐⭐⭐

Ohtani is projected to go just one or two innings tonight, which is why we're getting great value for this play. My confidence is through the roof for this prop regardless of how long Ohtani stays on the mound, however.

As you'll read in our best NRFI bets today piece, Ohtani absolutely owns this Padres lineup. Across 52 plate appearances against the Japanese superstar, San Diego is striking out at a 30.8% clip - and that's including guys like Fernando Tatis Jr., who's 0-3 with a K of his own.

The adrenaline will be pumping for Shohei tonight, and I wouldn't be surprised if we see an uptick in velocity as a result. Let's ride the Over as part of our best Ohtani prop bets, which we also feature in our Padres vs. Dodgers predictions.

✅ Best odds: +110 via Caesars ($10 pays $11)

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🔥 Shohei Ohtani Over 1.5 bases ⭐⭐⭐⭐

Ohtani has a .370 xBA against Dylan Cease across 22 at-bats, which should be enough to sway you into taking the Over on his total bases. But if it's not, let's sweeten the pot a bit here - the former MVP also has three home runs against Cease in his career, which is why we're riding him in our MLB home run predictions tonight. This play could cash early on, and I'd play it all the way down to -115.

✅ Best odds: -105 via BetMGM ($10 pays $9.52)

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🔥 Shohei Ohtani Over 0.5 RBI ⭐⭐⭐⭐

The math is mathing on this one: Ohtani plays a huge role in this Dodgers offense, he sees the ball out of Cease's hand well, the volume of at-bats will be there as the leadoff man, and he has five hits in his last six plate appearances.

He's one of the hottest hitters in baseball right now, and with the bottom of the Dodgers' order consistently setting the table for him (Andy Pages, anyone?), we're riding him to register a RBI as part of our best Shohei Ohtani picks tonight. These odds are just too good to pass up, and I'd play it to +115.

✅ Best odds: +130 via Caesars ($10 pays $13)

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📊 Best Shohei Ohtani player props today

Looking for more Shohei Ohtani props for tonight? We've got you covered.

💰 Latest Padres vs. Dodgers odds & betting lines

Here are the latest odds and betting insights via BetMGM for tonight's game:

• The Dodgers remain -160 favorites with roughly an hour until first pitch, and 82% of all moneyline bets have been placed on favorite Los Angeles
• Bettors are expecting a low-scoring affair with 57% of bets coming on Under 9, which is juiced to -115 odds

💡 More MLB predictions today

• Best NRFI bets today
• Home run predictions
• Shohei Ohtani player props
• Angels vs. Yankees predictions
• Padres vs. Dodgers predictions

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