Tiger-Cats vs. Roughriders Prediction, Expert Picks & Odds: Another Explosive Game in Rematch

For the second straight week, the Saskatchewan Roughriders and Hamilton Tiger-Cats will clash, and we're offering our top Tiger-Cats vs. Roughriders predictions based on the best CFL odds.
The best game of the CFL season thus far happened in Week 2 when the Saskatchewan Roughriders (2-0) managed to score 10 points in under a minute to beat the Hamilton Tiger-Cats (0-2). The two teams meet again for the second straight week on Sunday at 7 p.m. ET (TSN/RDS, CFL+), this time from Mosaic Stadium in Regina, Sask.
The Roughriders are 2.5-point home favorites in the rematch after last week's comeback and continue to rise in the Grey Cup odds, led by CFL Most Outstanding Player odds contenders Trevor Harris and A.J. Ouellette.
Tiger-Cats vs. Roughriders prediction
Odds via our best sports betting sites; pick confidence based on a 1-to-5-star scale.
Over 50.5 ⭐⭐⭐
If last week's game between these two was any indication, points will be scored and defense will not be played. In Week 2, the Riders and Ti-Cats combined for 63 points in a 33-30 win for Saskatchewan. While it took the boys in green until the second half to come alive, they easily exposed a Hamilton defense that's been struggling all season.
Hamilton's allowing the second-most points per game in the CFL (32.5) and the second-highest QB rating (120.7). It was pretty clear as Saskatchewan's comeback was happening that this Hamilton secondary has issues, something we saw in its 32-24 loss to the Calgary Stampeders in Week 1. Harris showed he's still one of the best passers in the league when healthy and managed to throw for 390 and two scores against the Tiger-Cats.
I'd expect much of the same with Hamilton's inability to cover Kian Schaffer-Baker and Jerreth Sterns, who combined for 221 receiving yards last week. Between those two and Shawn Bane, Saskatchewan's got a scary trio of WRs. And while Ouellette has had a slow start to the year, he's still one of the best backs in the CFL after rushing for over 1,000 yards last season.
To keep up with a Saskatchewan attack that's averaging 31 per game, and cover for its flimsy defense, Hamilton will have to do what it's had to all season to stay in games: score points. Despite leading the league in yards per game (439) while putting up 27 points per game, the Tiger-Cats haven't won yet. It's hard to blame Bo Levi Mitchell, who at 34 is still gun-slinging.
Mitchell's already thrown for 680 yards in two games, including 380 with three scores last week against the Riders. He's not alone in leading this offense though with All-Star Tim White, who will surely want to make up for last week's costly drop. The Tiger-Cats are loaded with other playmakers, too, that can help expose a Saskatchewan defense allowing the second-most passing yards per game (358).
The odds imply a 52.61% probability the Over hits, according to our odds converter, with a $10 bet paying out $9.01.
Best odds: -111 via Betway
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Tiger-Cats vs. Roughriders first team to score
Roughriders (-141)
Given how explosive both of these passing attacks can be, this is a tough market to bet into. In last week's game, the Tiger-Cats struck first with a 13-yard field goal, but the Riders responded by scoring the first TD of the game - a 24-yard pass from Harris to Schaffer-Baker. With the home crowd at Mosaic behind them, I'm leaning towards Saskatchewan putting points on the board first this time around.
At this point, Harris is a more consistent passer than Mitchell, who can be volatile with his willingness to let it rip. The emergence of Sterns also makes the Riders offense so much more dangerous, and Ouellette is bound to pop sooner rather than later. Saskatchewan kicker Brett Lauther is also solid from 40-plus yards, he's 14-for-17 since 2023.
Tiger-Cats vs. Roughriders odds
Tiger-Cats vs. Roughriders odds via Betway as of Friday at 11:30 a.m. ET.
Teams | Moneyline | Spread | Total |
---|---|---|---|
Roughriders | -152 | -2.5 (-111) | Over: 50.5 (-111) |
Tiger-Cats | +125 | +2.5 (-111) | Under: 50.5 (-111) |
It looked like Hamilton would cruise to an easy cover in last week's game between these two teams. The Tiger-Cats were up 20-7 at halftime and had a 30-20 lead with just over five minutes to go, but somehow the Riders cashed the moneyline as an underdog. I'm sort of surprised they're not favored by more at home after last week, especially because they're 2-0 ATS while Hamilton is 0-2.
Unlike the spread, this total makes plenty of sense given how much scoring both teams have been doing and how frail their defenses have been at times. With it set to be a perfect day, these two passing attacks should really light up the scoreboard. Both teams are 2-0 to the Over this season.
Tiger-Cats vs. Roughriders game info
- When: Sunday, June 23 (7 p.m. ET)
- Where: Mosaic Stadium (Regina, Sask.)
- How to watch: TSN/RDS, CFL+
- Weather: 71 degrees, 16-mph winds, 20% chance of precipitation
- Favorite: Roughriders -2.5 (-111 via Betway)
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