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Best 76ers vs. Knicks Odds, NBA Player Props & Score Predictions
Pictured: Philadelphia 76ers forward Paul George drives against New York Knicks guard Josh Hart during. Photo by Bill Streicher via Imagn Images.

The Philadelphia 76ers are crumbling as they travel to face off against the New York Knicks on Wednesday while looking to halt an eight-game losing streak.

My 76ers vs. Knicks prediction and player props lock in on the woes of Tyrese Maxey for Philadelphia, and I examine a highly productive pair recently for New York.

Tipoff from Madison Square Garden in New York is at 7 p.m. ET (ESPN).

💰 Best 76ers vs. Knicks predictions & NBA player props tonight: Feb. 26

Here are my best 76ers vs. Knicks predictions and player props for tonight's NBA matchup with my pick confidence based on a 1-to-5-star scale. Be sure to check out the rest of our NBA picks along with our guide on how to bet on the NBA.    

  • Game pick: Knicks to cover -10.5 (-105 via BetMGM) ⭐⭐⭐⭐
  • Tyrese Maxey player prop pick: Under 27.5 points (-106 via Caesars) ⭐⭐⭐
  • Josh Hart player prop pick: Over 32.5 points + rebounds + assists (-110 via FanDuel) ⭐⭐⭐⭐
  • Quentin Grimes player prop pick: Over 12.5 points (-122 via FanDuel) ⭐⭐⭐

📊 76ers vs. Knicks pick & odds: Who will win tonight's NBA matchup?

As of Wednesday afternoon, the Knicks are favored by 10.5 points to beat the 76ers in tonight's NBA matchup at 7 p.m. ET from Madison Square Garden in New York. I predict the Knicks will beat the 76ers and cover the spread (-10.5).

🔢 76ers vs. Knicks odds & betting lines

Here are the latest 76ers vs. Knicks odds and betting lines from our best live betting sites.

🎯 76ers vs. Knicks score prediction: Knicks 124, 76ers 110

The Knicks have struggled on defense as of late, but the team still sports one of the best offenses in the Association. Spearheaded by the dynamic duo of Jalen Brunson and Karl-Anthony Towns, New York’s roster is loaded with talent on both ends of the court. Towns is banged up, but the Knicks will still be dominant even if he’s sidelined.

Philadelphia will be without Joel Embiid, and the Sixers’ supporting cast has dealt with several key injuries throughout the season. Philadelphia has failed to get into a rhythm on offense, and a team once heralded for its strong defense has faltered. 

The talent disparity is too great to ignore, and the Knicks should have no problem covering at home. After three devastating losses - each worse than the last - the Sixers may be looking ahead to next season, which gives them little motivation to keep this one close.

I predict the Knicks will beat the 76ers by a final score of 124 to 110.

Best bet: Knicks -10.5 (-105 via BetMGM)

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💰 Best 76ers vs. Knicks player prop bet odds & expert picks: Feb. 26

Here are my best 76ers vs. Knicks player prop bet odds and expert picks for tonight's NBA matchup. You can also check out our NBA player prop odds tool for the latest NBA odds at the best legal sportsbooks in your region.    

🏀 Best Tyrese Maxey prop pick: Under 27.5 points ⭐⭐⭐

Best odds: -106 via Caesars ($10 to win $9.43)

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Maxey has done all he can to keep the Sixers afloat this season, but despite some Herculean efforts, the team continues to struggle. Philly has lost eight in a row, and their last three post All-Star break have been devastating.

Philly lost by 20 to the Boston Celtics before losing to the Brooklyn Nets on a buzzer-beater. The team responded with a 32-point drubbing at the hands of the Chicago Bulls, who led by 50 at one point in the fourth quarter.

Maxey has hit the Over on this line in 27 of 49 games this season, but he’s trending in the wrong direction. He’s gone Over just twice across his last six games. Over his last four, he’s averaged just 16.3 points and attempted 10 or fewer shots three times.

Despite his assertion that he’s going to remain competitive every time he’s on the court, Maxey has got to be exhausted at this point in the season. The Sixers’ season is going down the tubes, and his lack of aggression on offense suggests Maxey may not be fully engaged.

I’m not convinced that his recent streak of poor performances is just a cold spell. Shooters shoot their slumps, but that hasn’t been the case for Maxey. We’ll take the Under here as the Sixers go up against an Eastern Conference powerhouse on the road in a game that could get ugly early.

📊 Best Tyrese Maxey prop bet odds

🏀 Best Josh Hart prop pick: Over 32.5 points + rebounds + assists ⭐⭐⭐⭐

Best odds: -110 via FanDuel ($10 to win $9.09)

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Hart has been on an absolute tear this season, posting 14.8 points, 9.7 rebounds and 5.8 assists per game. The points are just slightly off his career-best, but the boards and assists are easily the most of his career.

Hart is averaging 30.3 PRA per game this season, but he’s been even better over his last eight. In that span, he’s averaged 35.3 PRA, hit the Over four times, and delivered exactly 32 PRA in another.

Hart has compiled 33 or more PRA in three straight games heading into tonight’s tilt, and he’s in line for a favorable matchup. Hart averaged 37.5 PRA across two prior matchups with the Sixers this season, posting two triple-doubles and hitting the Over in both.

The absence of Embiid should be a boon for Hart’s rebound numbers, and the potential absence of Towns could offer additional scoring and rebounding opportunities on the offensive end.

📊 Best Josh Hart prop bet odds

🏀 Best Quentin Grimes prop pick: Over 12.5 points ⭐⭐⭐

Best odds: -122 via FanDuel ($10 to win $8.20)

Grimes has played a big role for the Sixers since landing with the team shortly before the All-Star break. In seven games with Philly, he's averaged 14.9 points in 32.1 minutes per game.

In his last game, he scored only nine points in 24 minutes. He left Monday’s matchup with the Bulls early due to a head contusion. Grimes has hit the Over in four of seven games, with Philly even counting that performance.

Grimes has been Philadelphia’s fourth-leading scorer since joining the team. However, Embiid will be out tonight, placing more offensive responsibility on Paul George, Maxey, and Grimes. The Knicks have allowed the seventh-most points to opposing SGs this season, at 23.1, and the fourth-most over the last seven, at 25.6.

📊 Best Quentin Grimes prop bet odds

🚑 76ers vs. Knicks injuries

Here are the latest injuries for tonight's 76ers vs. Knicks matchup, which will update in real time.

📺 How to watch 76ers vs. Knicks tonight

📅 Date: Wednesday, Feb. 26
🕗 Time: 7 p.m. ET
📍 Location: Madison Square Garden (New York)
📺 TV: ESPN

❓ 76ers vs. Knicks FAQs

Who is favored to win 76ers vs. Knicks?

The Knicks are -420 favorites to win which carries at 80.77% implied win probability.

What are the odds for 76ers vs. Knicks?

The Knicks are favored by 10.5 points, with a total set at 230.5.

What time is 76ers vs. Knicks tonight?

Tipoff from Madison Square Garden is at 7 p.m. ET.

How to watch 76ers vs. Knicks

You can watch 76ers vs. Knicks on ESPN.

🏀 Best NBA betting sites

Looking to bet on the NBA tonight? Here are our best NBA betting sites as determined by our expert team at Sportsbook Review, along with our best sportsbook promos available for tonight's NBA games.

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