Alabama vs. BYU Prediction, Odds & Preview Tonight: Best Picks for NCAA Tournament Sweet 16

The No. 6 seed BYU Cougars (26-9) will look to keep up with the No. 2 seed Alabama Crimson Tide (27-8) as the two squads kick off today's NCAA Tournament Sweet 16 action. We dig into whether they can with our Alabama vs. BYU prediction, odds, and preview as part of our March Madness predictions.
The Crimson Tide, among the March Madness odds contenders, are the 4.5-point betting favorites when the action from Prudential Center in Newark, N.J., gets underway at 7:09 p.m. ET (CBS). But we think this Cougars squad can pull an outright upset.
🏀 Alabama vs. BYU prediction & picks for today
Here are my best Alabama vs. BYU predictions for the Sweet 16 of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:
✅ Against the spread pick: BYU +4.5 (-110 via FanDuel) vs. Alabama ⭐⭐⭐⭐⭐
🔥 Best player prop bet: Mark Sears Under 4.5 assists (+110 via bet365) ⭐⭐⭐
🎯 Exact score prediction: BYU 94, Alabama 90 (+20000 via DraftKings)
👉 Want more picks? Check out our latest college basketball picks and the rest of our March Madness Sweet 16 predictions.
Alabama vs. BYU betting insights
- There's nearly even action against the spread during the hours before tipoff, with Alabama at -4.5 narrowly getting more attention at 54%
- We see a similar story with the total while it sits at 175.5 through bet365, as the Over is generating slightly more action at 53%
- The spread has returned to where it opened, but it did shift to -5.5 for much of Tuesday morning
🏆 Best Alabama vs. BYU pick, player prop bet & score prediction
Our NEW college basketball player prop odds tool can help you find the best odds for any March Madness market across legal sportsbooks in your area!
✅ BYU to cover the spread: +4.5 ⭐⭐⭐⭐⭐
Alabama plays one of the most unique styles of any D-I college basketball team, blending an up-tempo attack with elite spacing and shooting and getting almost all of its shots from 3-point range or at the rim. While many teams struggle with dealing with the Crimson Tide’s modernized philosophies, that plays right into BYU’s hands. The Cougars are arguably the closest mirror image of Alabama as any team in the country.
BYU will not mind getting up and down with Alabama, and the Cougars are built to expose the Crimson Tide’s defensive inefficiencies, as Alabama has allowed 90-plus points in five of its last 11 games. This line feels overinflated after Alabama beat a horrifically poor-shooting Saint Mary’s team that had gone 12-for-68 from 3-point range over its last four games.
BYU ranks 18th in percentage of its points it gets from beyond the arc, and will pose much bigger problems for Alabama.
📊 Best odds: -110 via FanDuel ($10 to win $9.09)
🔥 Mark Sears Under 4.5 assists ⭐⭐⭐
Alabama assisted on 15 of 29 made field goals in its win over Saint Mary’s. And the Crimson Tide did not necessarily need to zip the ball around on offense, as they scored 35 of their 42 first-half points on possessions with two or fewer passes.
Sears has the ball in his hands a lot, ranking 11th in SEC play in percentage of his team’s possession rate and third in assist rate. But he also has four or fewer assists in three of the last four games and should take the lion’s share of the shots against a Cougars defense that allows opponents to shoot 35% from beyond the arc.
This is also one of my favorite Alabama vs. BYU player prop picks.
📊 Best odds: +110 via bet365 ($10 to win $11)
🎯 Score prediction: BYU 94, Alabama 90
BYU has won and covered its last six games where both teams have scored 80-plus points. Thus, not only am I supremely confident in taking the +4.5 points, but I will sprinkle a little on the Cougars’ moneyline odds (+170 at DraftKings) as well.
I’m predicting a final score of BYU 94, Alabama 90.
📊 Best odds: +20000 via DraftKings ($10 to win $2000)
🤖 Alabama vs. BYU AI prediction
For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for Alabama vs. BYU. Our AI prediction projects a final score of Alabama 81, BYU 67.
🖥️ AI score prediction: Alabama 81, BYU 67
- With a potent offense, Alabama is built to outscore opponents. BYU’s defense will struggle to contain Alabama’s up-tempo game, which could lead to fast-break points and easy baskets.
- Alabama is one of the best rebounding teams in the nation, especially on the offensive glass. BYU will need to limit second-chance opportunities, but Alabama’s size and athleticism will likely overwhelm the Cougars.
- Alabama’s superior offense, rebounding, and overall depth make it a heavy favorite in this matchup. BYU may keep it competitive early, but Alabama's pace and talent should take control by the second half.
🤔 Betting takeaway: ChatGPT's AI prediction would mean Alabama covering the spread (-4.5) and a total of Under 174.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.
📊 Live Alabama vs. BYU odds
Follow the latest live March Madness college basketball odds and real-time NCAA Tournament scores for the Sweet 16.
🔢 Alabama vs. BYU opening odds
- Spread: Alabama -4.5 (-112) | BYU +4.5 (-108)
- Moneyline: Alabama -200 | BYU +168
- Over/Under: Over 173.5 (-115) | Under 173.5 (-105)
Alabama vs. BYU line movement
All movement prior to tipoff via bet365.
Spread
The spread is now mostly back to where it started, with Alabama as the -4.5 favorite. However, it shifted briefly to -5.5 on Tuesday morning.
Total
The total started at 174.5 before gradually climbing to 177 by around noon ET today. It's since come down from that peak and sits at 175.5.
Moneyline
The moneyline has taken a bit of a journey, though it still hasn't moved far from the starting point. Alabama opened as the -200 favorite before lengthening to -185. Gradually throughout the week the line fell again, moving as short as -230 for the Crimson Tide. It now rests at -210.
📺 How to watch Alabama vs. BYU: NCAA Tournament Sweet 16
📅 Date: Thursday, March 27
🕗 Time: 7:09 p.m. ET
📍 Location: Prudential Center (Newark, N.J.)
📺 TV: CBS
💻 Streaming: March Madness Live
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