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Duke vs. Baylor Prediction, Odds & Preview Today: March Madness Best Bets March 23
Pictured: Duke Blue Devils forward Cooper Flagg passes the ball. Photo by Zachary Taft via Imagn Images

Today's NCAA Tournament second-round game from Lenovo Center in Raleigh, N.C., (2:40 p.m. ET, CBS) pits the No. 1 seed Duke Blue Devils (32-3) against the No. 9 seed Baylor Bears (20-14). 

While Baylor - the 12.5-point betting underdog at BetMGM - should provide more resistance than Mount St. Mary's, we don't foresee any issues for the Blue Devils in our Duke vs. Baylor prediction, odds, and preview. 

We're banking on the pro-Blue Devils crowd in Raleigh to add even more fuel to their raging fire. 

🏀 Duke vs. Baylor prediction & picks today

Here are my best Duke vs. Baylor predictions for the second round of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:

✅ Against the spread pick: Duke -11.5 (-118 via FanDuel) vs. Baylor ⭐⭐⭐
🔥 Best team prop bet: Duke team total Under 78.5 points (
-125 via DraftKings) ⭐⭐⭐
🎯 Exact score prediction: Duke 75, Baylor 61 (+14000 via DraftKings)

👉 Want more picks? Check out our latest college basketball picks and the rest of our March Madness second-round predictions.

🔢 Duke vs. Baylor updated betting action 

The below updated betting action is via BetMGM.

  • 58% of the bets are on the Blue Devils (-12.5) to cover
  • 82% of the bets are on the Over (144.5)
  • Duke opened as 11.5-point betting favorites. That line has since increased to 12.5 points

🏆 Best Duke vs. Baylor pick, player prop bet & score prediction

Our NEW college basketball player prop odds tool can help you find the best odds for any March Madness market across legal sportsbooks in your area!

✅ Duke to cover the spread: -11.5 ⭐⭐⭐

There was a significant question mark tied to Duke's roster entering the NCAA Tournament, as it was unknown how recovered Cooper Flagg was from an ankle injury suffered during the ACC tournament.

Flagg looked just fine while scoring 14 points in 22 minutes and grabbing seven rebounds. Jon Scheyer was able to bring his Wooden Award odds candidate back slowly given the team’s dominant win. Our Shane Jackson dives into Flagg's outlook further in his Cooper Flagg odds and player prop bets.

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Baylor will likely look to draw Duke’s Khaman Maluach away from the paint while pulling Norchad Omier out to the perimeter.

But the Bears won't be able to exploit many other defensive mismatches, as Duke’s elite length as the tallest team in the country should bother Baylor’s shooters.

This is a three-star play, as Duke’s 20-mile trip to Raleigh is the shortest that any NCAA Tournament team needs to make to its regional site. I expect a raucous North Carolina crowd will spur Duke on to a win and cover.

📊 Best odds: -118 via FanDuel ($10 to win $8.47)

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🔥 Duke team total Under 78.5 points ⭐⭐⭐

Duke ended the regular season while notching 80-plus points in seven consecutive games. But it hasn't exceeded this projected total in any tournament game so far, including conference clashes.

Baylor boasts a Duke transfer on its roster in Jeremy Roach who knows Scheyer’s playbook. So if Bears head coach Scott Drew is going to mix up his defenses, Roach should be able to provide insight into Duke’s tendencies.

This is a three-star play, as the Bears have held 14 straight opponents to 76 or fewer points.  

📊 Best odds: -125 via DraftKings ($10 to win $8)

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🎯 Score prediction: Duke 75, Baylor 61

The Blue Devils have covered nine of their last 11 games while recording four 33-plus-point wins during that span. That type of dominance is why I’m predicting a final score of Duke 75, Baylor 61. 

📊 Best odds: +14000 via DraftKings ($10 to win $1400)

🤖 Duke vs. Baylor AI prediction

For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for Duke vs. Baylor. Our AI prediction projects a final score of Duke 76, Baylor 71.

🖥️ AI score prediction: Duke 76, Baylor 71

  • Both teams boast dynamic guards who can take over games. Which team’s backcourt performs better under pressure could be the deciding factor in this contest.
  • Duke’s suffocating defense and frontcourt depth should limit Baylor’s offensive flow, particularly in the paint, where it will hold a distinct advantage.
  • Both teams are battle-tested, but Duke holds the slight edge in tournament experience and defensive versatility. Look for Scheyer’s squad to lock down in crunch time and secure the win.

🤔 Betting takeaway: ChatGPT's AI prediction would mean Baylor covering the spread (+11.5) and a total of Over 145.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.

📊 Live Duke vs. Baylor odds

Follow the latest live March Madness college basketball odds and real-time NCAA Tournament scores for the second round.

Latest Duke vs. Baylor odds

Here are the latest odds for Duke vs. Baylor from BetMGM ahead of tipoff:

Spread

Duke is a 12.5-point betting favorite against Baylor. Both sides are juiced at the standard -110 (52.38% implied probability).

Total

The Duke vs. Baylor betting total decreased is 144.5, up from 143.5. Both sides are juiced to -110 (52.38% implied probability).

Moneyline

Duke is a -800 moneyline favorite with an implied win probability of 88.89%. Baylor is the +550 underdog, carrying a 15.38% implied probability.

🔢 Duke vs. Baylor opening odds

  • Spread: Duke -11.5 (-114) | Baylor +11.5 (-106)
  • Moneyline: Duke -780 | Baylor +530
  • Over/Under: Over 145.5 (-105) | Under 145.5 (-115)

Today's March Madness game picks

Here are today's best game previews and predictions:

📺 How to watch Duke vs. Baylor: NCAA Tournament second round

📅 Date: Sunday, March 23
🕗 Time: 2:40 p.m. ET
📍 Location: Lenovo Center (Raleigh, N.C.)
📺 TV: CBS
💻 Streaming: March Madness Live

💰 March Madness betting odds pages

👑 Best March Madness betting sites

Ready to place your March Madness bets? Check out the best March Madness betting promos from the best March Madness betting sites as determined by our expert team at Sportsbook Review.

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