Iowa State vs. Ole Miss Prediction, Odds & Preview Today: NCAA Tournament Best Bets
The No. 3 seed Iowa State Cyclones (25-9) meet the No. 6 seed Ole Miss Rebels (23-11) in today's NCAA Tournament second round at 7:45 p.m. ET (TruTV) from Rocket Arena in Cleveland.
The Cyclones are 5.5-point favorites to advance in the South Region of the March Madness bracket after dominating their first-round matchup against the Lipscomb Bisons. We discuss whether they can hold off the Rebels in our Iowa State vs. Ole Miss prediction, odds, and preview as part of our March Madness predictions.
🏀 Iowa State vs. Ole Miss prediction & picks today
Here are my best Iowa State vs. Ole Miss predictions for the second round of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:
✅ Against the spread pick: Ole Miss +5.5 (-110 via BetMGM) vs. Iowa State ⭐⭐⭐⭐
🔥 Best team prop bet: Ole Miss Over 70.5 points (-110 via DraftKings) ⭐⭐⭐⭐
🎯 Exact score prediction: Iowa State 79, Ole Miss 77 (+19000 via DraftKings)
👉 Want more picks? Check out our latest college basketball picks and the rest of our March Madness second-round predictions.
🔢 Iowa State vs. Ole Miss updated betting action
The below updated betting action is via BetMGM.
- Bettors at BetMGM are narrowly favoring Iowa State, with the Cyclones generating 56% of the action as the -5.5 favorites
- The Over is getting 60% of the action while listed at 144
- The spread has stayed stagnant, with Iowa State consistently listed at -5.5
🏆 Best Iowa State vs. Ole Miss pick, player prop bet & score prediction
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✅ Ole Miss to cover the spread: +5.5 ⭐⭐⭐⭐
The Rebels barely survived a furious comeback from the North Carolina Tar Heels in the first round after holding a lead as high as 22. The Tar Heels then cut that to two, but the Rebels held on for the seven-point victory. Rather than dwell on the near collapse, I’ll focus on what the Rebels did well.
The Rebels shot 40% from beyond the arc while outrebounding the Tar Heels 40-34. Sean Pedulla was excellent, leading the way with 20 points while making huge shots every time the Rebels were in need. The Rebels have now won four of their last six games, and their only two losses during that stretch were to the highly talented Florida Gators and Auburn Tigers.
Meanwhile, the Cyclones were essentially perfect in their first game. They shot 58.3% from the field while pulling away early and never looking back.
However, I’m not putting much stock in that blowout. The Cyclones didn't feel the absence of Keshon Gilbert much in the first round. But that will change now, as the battle-tested Rebels should keep this close and potentially pull off the upset.
📊 Best odds: -110 via BetMGM ($10 to win $9.09)
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🔥 Ole Miss Over 70.5 points ⭐⭐⭐⭐
The Cyclones are allowing an average of 67.7 points per game, and they gave up 96 points to the BYU Cougars in the matchup before their impressive victory over Lipscomb. They’ve held three of their last four opponents to fewer than 60 points, though that's connected more to inferior competition.
The Rebels dropped exactly 71 points in the first round, even while facing North Carolina's weak defense. However, this game is going to be much closer throughout. The Rebels took a huge lead against the Tar Heels, which really slowed down the pace of the game.
But the Rebels have also scored at least 71 points in 13 of their last 14 outings. The team is consistent despite not lighting up the scoreboard offensively. And while the Cyclones are good defensively, the team's quality isn't good enough to prevent the Rebels from getting to their average of 77.0 points per game.
📊 Best odds: -110 via DraftKings ($10 to win $9.09)
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🎯 Score prediction: Iowa State 79, Ole Miss 77
Both of these teams rank in the top 70 in scoring, with the Cyclones averaging 80.4 points per game, and the Rebels averaging 77.0. Both teams played well offensively in the first round, and the Rebels proved they can slow down a very good offense, even if the game was scary down the stretch.
However, the Rebels are allowing over 71 points per game, so the Cyclones will get close to their season average even without Gilbert. This is going to be a one-possession matchup either way, but I’ll give the slight edge to the higher seed.
📊 Best odds: +18000 via DraftKings ($10 to win $1,800)
🤖 Iowa State vs. Ole Miss AI prediction
For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for Iowa State vs. Ole Miss. Our AI prediction projects a final score of Iowa State 77, Ole Miss 70.
🖥️ AI score prediction: Iowa State 77, Ole Miss 70
- The Cyclones are recognized for their balanced play, combining strong offense with solid defense. Their ability to adapt without key players showcases the team's depth and resilience.
- Ole Miss has been achieving notable victories under head coach Chris Beard, including wins against top-seeded teams like Tennessee and Alabama.
- Beard's previous success, notably leading Texas Tech to the Final Four in 2019, adds a wealth of tournament experience to Ole Miss.
🤔 Betting takeaway: ChatGPT's AI prediction would mean Iowa State covering the spread (-5.5) and a total of Over 145.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.
📊 Live Iowa State vs. Ole Miss odds
Follow the latest live March Madness college basketball odds and real-time NCAA Tournament scores for the second round.
Latest Iowa State vs. Ole Miss odds
Here are the latest odds for Iowa State vs. Ole Miss from BetMGM ahead of tipoff:
Spread
Iowa State has remained the -5.5 favorite since lines were first posted, and the lack of movement is surely the result of nearly even action on both sides.
Total
The total has been switching between 145.5 and 144.5, and it now sits at the latter number in the hours before tipoff.
Moneyline
There's been moderate moneyline movement, with Iowa State opening as the -225 favorite before shortening slightly to -235. The latter implies a probability of 70.15%.
🔢 Iowa State vs. Ole Miss opening odds
- Spread: Iowa State -5.5 (-110) | Ole Miss +5.5 (-110)
- Moneyline: Iowa State -230 | Ole Miss +190
- Over/Under: Over 145.5 (-110) | Under 145.5 (-110)
📺 How to watch Iowa State vs. Ole Miss: NCAA Tournament second round
📅 Date: Sunday, March 23
🕗 Time: 7:45 p.m. ET
📍 Location: Fiserv Forum (Milwaukee)
📺 TV: TruTV
💻 Streaming: March Madness Live
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