LSU vs. San Diego State Prediction, Odds & Preview Today: Women's March Madness Best Bets

The No. 3 seed LSU Tigers will meet the No. 14 San Diego State Aztecs in today's womenโs NCAA Tournament first round at 10:15 p.m. ET (ESPN) at Pete Maravich Assembly Center in Baton Rouge, La.
The Tigers are 26.5-point betting favorites to advance in the Spokane 1 Region of the women's March Madness bracket. However, we expect the Aztecs to stay within striking distance in our LSU vs. San Diego State prediction, odds, and preview as part of our women's March Madness predictions.
๐ LSU vs. San Diego State prediction & picks today
Here are my best LSU vs. San Diego State predictions for the first round of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:
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Against the spread pick: San Diego State +26.5 (-110 via BetMGM) vs. LSU โญโญ
๐ฅ Best player prop bet: Aneesah Morrow to score 20-plus points (-150 via FanDuel) โญโญโญ
๐ฏ Exact score prediction: LSU 83, San Diego State 62 (+16000 via DraftKings)
๐ Want more March Madness action? Check out the rest of our college basketball picks for both the men's and women's NCAA tournament.
๐ Best LSU vs. San Diego State pick, player prop bet & score prediction
Our NEW college basketball player prop odds tool can help you find the best odds for any March Madness market across legal sportsbooks in your area!
โ San Diego State to cover the spread: +26.5 โญโญ
This spread is as low as 25.5 at FanDuel, but the rest of our best sportsbooks are still trading this line at 26.5. Iโm backing the Aztecs following their triple overtime win over Wyoming in the Mountain West Conference title game, which marked their eighth victory in a row.
This is more of a fade of the Tigers at such a big number. LSUโs best player, โโFlauโjae Johnson, is back in the lineup after missing the regular-season finale and the SEC tournament due to shin inflammation, and LSU - who are among the women's March Madness odds contenders - has lost three of its last four games.
The Tigers should still win by a comfortable margin, but Iโm not interested in laying the points with them in this one.
๐ Best odds: -110 via BetMGM ($10 to win $9.09)
๐ฅ Aneesah Morrow to score 20-plus points โญโญโญ
There are two reasons why I like LSU forward Morrow to have a big day:
- San Diego State is undersized
- Flauโjae Johnson hasnโt played since Feb. 27
Morrow has averaged 18.5 points per game this season but cleared this mark in two of her past three outings. She scored 36 points against Florida last Friday and says her conditioning is back after recovering from a foot injury in recent weeks.
The Tigers should lean on Morrow against SDSU.
๐ Best odds: -150 via FanDuel ($10 to win $6.67)
๐ฏ Score prediction: LSU 83, San Diego State 62
The 26.5-point betting spread feels a touch high based on LSUโs recent form and its best player returning from injury. But donโt get it twisted; the Tigers should still win comfortably.
๐ Best odds: +16000 via DraftKings ($10 to win $1,600)
๐ค LSU vs. San Diego State AI prediction
For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for LSU vs. San Diego State. Our AI prediction projects a final score of LSU 82, San Diego State 62.
๐ฅ๏ธ AI score prediction: LSU 82, San Diego State 62
- The Tigers are led by junior guard Flau'jae Johnson, who averages 18.9 points, 5.8 rebounds, and 1.6 steals per game.
- The Aztecs are led by guards Veronica Sheffey and Naomi Panganiban, who average 11.4 and 10.5 points per game, respectively.
- LSU forces turnovers at a high clip and will likely pressure SDSUโs ball-handlers like Sheffey and Panganiban.
๐ค Betting takeaway: ChatGPT's AI prediction would mean San Diego State covering the spread (+26.5) and a total of Under 144.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.
๐ Live LSU vs. San Diego State odds
Follow the latest women's March Madness odds for the NCAA Tournament.
๐ข LSU vs. San Diego State opening odds
- Spread: LSU -26.5 (-110) | San Diego State +26.5 (-110)
- Moneyline: LSU -50000 | San Diego State +3500
- Over/Under: Over 145.5 (-110) | Under 145.5 (-110)
๐บ How to watch LSU vs. San Diego State: Women's March Madness
๐
Date: Saturday, March 22
๐ Time: 10:15 p.m. ET
๐ Location: Pete Maravich Assembly Center (Baton Rouge, LA)
๐บ TV: ESPN
๐ป Streaming: March Madness Live
Today's best women's March Madness picks
Here are our other women's March Madness picks for today's first-round games:
- Iowa vs. Murray State prediction
- UConn vs. Arkansas State prediction
- Best Paige Bueckers odds, player props
- USC vs. UNC Greensboro prediction
- Best JuJu Watkin odds, player props
- LSU vs. San Diego State prediction
๐ฐ March Madness betting odds pages
March Madness odds | March Madness MVP odds |
Women's March Madness odds | March Madness MVP predictions |
Final Four odds | March Madness prop bets |
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