March Madness Bracket: Updated NCAA Tournament Predictions Entering Today's Sweet 16
There are just a few rounds left until March Madness crowns its king, and with every single bracket already busted, it's time to project the final 11 games from the Sweet 16 through the national championship.
Despite an extremely chalky field, our March Madness bracket and updated NCAA Tournament predictions entering the Sweet 16 focus on a few bold picks that could inject some chaos into an event usually known for plenty of it.
👉 Want more March Madness action? Check out the rest of our March Madness Sweet 16 predictions and stay up to date with the March Madness Sweet 16 odds and schedule.
🔮 Updated March Madness bracket: NCAA Tournament predictions entering Sweet 16
👉 Want more Sweet 16 action? Check out our March Madness Sweet 16 survivor picks, our latest March Madness odds, our Sweet 16 picks and Final Four predictions, and our March Madness second-chance brackets.
🍬 Sweet 16 picks
| Matchup | Pick | Moneyline odds | Game details |
|---|---|---|---|
| Alabama (2) vs. BYU (6) | BYU ❌ | +185 via Caesars | Thursday, March 27 at 7:09 p.m. ET (CBS) |
| Florida (1) vs. Maryland (4) | Florida ✅ | -285 via FanDuel | Thursday, March 27 at 7:39 p.m. ET (TBS/truTV) |
| Duke (1) vs. Arizona (4) | Duke ✅ | -450 via FanDuel | Thursday, March 27 at 9:39 p.m. ET (CBS) |
| Texas Tech (3) vs. Arkansas (10) | Texas Tech ✅ | -235 via Caesars | Thursday, March 27 at 10:09 p.m. ET (TBS/truTV) |
| Michigan State (2) vs. Ole Miss (6) | Ole Miss | +150 via DraftKings | Friday, March 28 at 7:09 p.m. ET (CBS) |
| Tennessee (2) vs. Kentucky (3) | Tennessee | -184 via FanDuel | Friday, March 28 at 7:39 p.m. ET (TBS/truTV) |
| Auburn (1) vs. Michigan (5) | Auburn | -385 via FanDuel | Friday, March 28 at 9:39 p.m. ET (CBS) |
| Houston (1) vs. Purdue (4) | Houston | -345 via FanDuel | Friday, March 28 at 10:09 p.m. ET (TBS/truTV) |
🔵 Boldest pick: BYU over Alabama
Without any real magic in the first two rounds of the NCAA Tournament, our March Madness Sweet 16 Cinderella watch is focused on power conference programs that are clear underdogs. My favorite bold pick of the Sweet 16 is BYU taking down Alabama in a game I suspect could end up with the highest total of March Madness.
Both teams love to shoot threes, play defense like it's optional, and are among the top 10 teams in the country in adjusted offensive efficiency, per KenPom. If BYU's Richie Saunders plays against Alabama the way he did against Wisconsin, the Crimson Tide could be in trouble.
The Cougars' run to the Sweet 16 has also benefited from out-of-nowhere 3-point shooting improvements from Egor Demin, who we highlighted as a March Madness star who helped his NBA draft stock after the first two rounds.
Playing such similar styles, I think it will be much more of a toss-up than the odds suggest, especially with how Alabama struggled against No. 15 seed Robert Morris in the first round.
📊 BYU's odds to beat Alabama in the Sweet 16: +185 via Caesars | Implied probability: 35.09%
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🎟️ Elite Eight predictions
| Projected matchup | Pick | Odds to win region | Game details |
|---|---|---|---|
| Auburn (1) vs. Ole Miss (6) | Auburn | -135 via DraftKings (South) | Saturday, March 29/Sunday March 30 |
| Florida (1) vs. Texas Tech (3) | Texas Tech | +320 via DraftKings (West) | Saturday, March 29/Sunday March 30 |
| Duke (1) vs. BYU (6) | Duke | -185 via FanDuel (West) | Saturday, March 29/Sunday March 30 |
| Houston (1) vs. Tennessee (2) | Houston | -110 via FanDuel (Midwest) | Saturday, March 29/Sunday March 30 |
🏴☠️ Boldest pick: Texas Tech over Florida
Is taking a No. 3 seed to reach the Final Four really that bold?
With how few upsets there have been and all four No. 1 seeds seemingly being a notch above the rest of the field, it sure is this season. Taking the Red Raiders to beat Florida, who came into March Madness as the hottest team in the country, is an extra spicy bet.
Florida's offense is spectacular with Walter Clayton Jr. leading the charge, but the Gators were nearly upset by No. 8 seed UConn in the second round, and Texas Tech has a more potent scorer than the Huskies. All-American JT Toppin is the key to this upset, and his physicality could prove challenging for this Florida defense.
He's not alone, either, with fellow frontcourt monster Darrion Williams, sharpshooter Chance McMillian expected to be back, and passing extraordinaire Elijah Hawkins. It helps Grant McCasland's team that it will have played only double-digit seeds to reach the Elite Eight, meaning the team might feel slightly less wear and tear than the Gators.
📊 Texas Tech's odds to win West region: +320 via DraftKings | Implied probability: 23.81%
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4️⃣ Final Four predictions
| Projected matchup | Pick | Odds to reach championship | Game details |
|---|---|---|---|
| Duke (1) vs. Houston (1) | Duke | +125 via FanDuel | Saturday, April 5 at 6:09 p.m./8:49 p.m. ET (CBS) |
| Auburn (1) vs. Texas Tech (3) | Auburn | +200 via FanDuel | Saturday, April 5 at 6:09 p.m./8:49 p.m. ET (CBS) |
🐯 Boldest pick: Auburn to reach national championship
It really goes to show how uninspiring the Sweet 16 field is if I'm claiming Auburn, the No. 1 overall seed in the whole dang tournament, is a bold choice to reach the championship. I only call it bold because I don't see any way Bruce Pearl's team wins March Madness with how it's played lately.
However, getting No. 5 seed Michigan and then potentially (based on my bracket) No. 6 seed Ole Miss and No. 3 seed Texas Tech would make the path to the title far easier than expected. The Tigers haven't played like a dominant force recently, and Johni Broome has not looked all that great in the NCAA Tournament.
Michigan could very well take Auburn down with its pair of bigs, Danny Wolf and Vladislav Goldin, offering a challenging matchup. But, despite the sporadic showing from some of their stars thus far, I have the Tigers winning thanks to their guard play.
📊 Auburn's odds to reach national championship: +200 via FanDuel | Implied probability: 33.33%
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🏆 March Madness winner prediction
| Projected matchup | Pick | March Madness odds | Game details |
|---|---|---|---|
| Auburn (1) vs. Duke (1) | Duke | +230 via bet365 | Monday, April 7 at 8:50 p.m. ET (CBS) |
😈 March Madness championship pick: Duke
It's been my pick from the start, and Duke has given me zero reasons to waver. This is the most talented team in the NCAA Tournament, which is why the Blue Devils are the March Madness odds favorites.
The crazy part is that Wooden Award odds favorite Cooper Flagg hasn't even had to light it up with how efficient teammates like Tyrese Proctor and Kon Knueppel have played. This is the most well-rounded team in the country, and it boasts the best two-way player in Flagg.
It's going to take a nearly flawless game to knock this Duke team out of the NCAA Tournament.
📊 Duke's March Madness championship odds: +230 via bet365 | Implied probability: 30.30%
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🧠 Sweet 16 expert picks
- Sweet 16 picks & Final Four predictions
- March Madness Sweet 16 Cinderella watch
- March Madness second chance brackets
- March Madness Sweet 16 survivor picks
- March Madness MVP odds and predictions
- March Madness Sweet 16 picks
- March Madness Sweet 16 predictions
- Latest March Madness odds
- March Madness Final Four odds
- 2025 March Madness stats
- March Madness long shots
- Who are the best players in the 2025 NCAA Tournament?
- One of these 8 teams will win the NCAA Tournament
🆚 Sweet 16 game predictions
- Michigan State vs. Ole Miss prediction
- Tennessee vs. Kentucky prediction
- Auburn vs. Michigan prediction
- Houston vs. Purdue prediction
💰 March Madness betting odds pages
| March Madness odds | March Madness MVP odds |
| Women's March Madness odds | March Madness MVP predictions |
| Final Four odds | March Madness prop bets |
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