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March Madness Odds & NCAA Tournament Betting Lines: Duke the Favorite After Bracket Reveal
Pictured: Duke Blue Devils center Khaman Maluach (9) holds the trophy and celebrates with head coach Jon Scheyer. Photo by Jim Dedmon-Imagn Images.

The bracket is complete and Duke remains the consensus betting favorite by the latest March Madness odds following Selection Sunday.

The Blue Devils cruised to an ACC tournament win even without star Cooper Flagg and that helped earn them the No. 1 seed in the East region. Duke entered Selection Sunday as a slight betting favorite over Auburn by the March Madness odds.

Study up on the odds below before filling out your March Madness bracket ahead of the first round of the NCAA Tournament.

πŸ“Š Live 2025 March Madness odds for all 68 teams

March Madness odds are from our best sports betting sites and update in real time. Throughout the NCAA Tournament, visit Sportsbook Review to get the best college basketball prop bets today.

Before locking in any of your picks to win March Madness, be sure to check out the March Madness betting promos and our March Madness bracket challenges. Futures bets will be paid out following the national championship game on Monday, April 7.

πŸ† March Madness odds 2025: Teams to watch

😈 Duke March Madness odds: +360

As the top seed in the East region, Duke will play its first-round matchup against the winner of American and Mount St. Mary's on Wednesday.

The Blue Devils will hope to have Wooden Award odds favorite Cooper Flagg back in the lineup for the NCAA Tournament after he was sidelined for the conclusion of the ACC tournament due to an apparent leg injury.

Best odds: +360 via BetMGM | $10 bet pays a $36 profit

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🐯 Auburn March Madness odds: +450

Auburn was awarded the No. 1 seed in the South region and also faces a play-in winner in the first round. If it survives the first round, Auburn will advance to face the winner of Louisville (8) vs. Creighton (9).

Auburn's first-round opponent will be the winner of Alabama State vs. Saint Francis on Tuesday.

Best odds: +450 via BetRivers | $10 bet pays a $45 profit

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🐊 Florida March Madness odds: +450

Florida is the top seed in the West region and draws a first-round matchup with Norfolk State on Friday. The Gators defeated Tennessee 86-77 in Sunday's SEC tournament final.

Best odds: +450 via bet365 | $10 pays a $45 profit

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πŸ›‘ Houston March Madness odds: +750

Houston draws SIU Edwardsville as the No. 1 seed in the Midwest region. That game will take place Thursday. 

The Cougars have won 13 straight games, including a 72-64 victory over Arizona in the Big 12 tournament final on Saturday.

Best odds: +750 via FanDuel | $10 bet pays a $75 profit

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🌊 Alabama March Madness odds: +1700

Alabama is the top second seed in the 2025 bracket, and lines up to potentially face Duke in the Elite Eight. The Crimson Tide's NCAA Tournament will begin against Robert Morris on Friday.

The Tide fell to Florida by a 104-82 score in the SEC tournament on Saturday.

Best odds: +1700 via DraftKings | $10 bet pays a $170 profit

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🧠 March Madness bracket tips

Here are our college basketball betting experts' best March Madness bracket tips:

πŸ“ˆ March Madness opening odds

March Madness opening odds via FanDuel.

  • Duke: +1100
  • Kansas: +1100
  • UConn: +1200
  • Houston: +1400
  • North Carolina: +1600
  • Kentucky: +1800
  • Alabama: +2000
  • Arizona: +2000
  • Baylor: +2000
  • Gonzaga: +2000
  • Michigan State: +2500
  • Purdue: +2500
  • Tennessee: +2500
  • Auburn: +3000
  • Iowa State: +3000
  • Texas: +3000
  • Creighton: +3500
  • Marquette: +3500
  • Arkansas: +4000

πŸ–¨οΈ March Madness bracket

You can download a March Madness bracket PDF right here to fill in with your projected NCAA Tournament field. We will have the official 2025 bracket on Selection Sunday.

Auburn, Duke, Houston, and Florida earned the four No. 1 seeds in the South, East, Midwest, and West regions, respectively.

πŸ”’ March Madness betting history

Here are the recent winners of March Madness and their preseason betting odds:

YearTeamPreseason odds
2023-24UConn+2000
2022-23UConn+8000
2021-22Kansas+1400
2020-21Baylor+800
2019-20Canceled 
2018-19Virginia+1350
2017-18Villanova+2700
2016-17North Carolina+1900
2015-16Villanova +2500
2014-15Duke+900
2013-14Connecticut +6500
2012-13Louisville+700

❓March Madness FAQs

Who is the March Madness 2025 favorite?

The Duke Blue Devils are the favorites to win the 2025 NCAA Tournament with +350 odds. Those odds imply a win probability of 22.22%.

When does March Madness start?

The First Four games of March Madness will be played on March 18 and 19. The first round of the NCAA Tournament will then be played March 20 and 21, followed by the second round on March 22 and 23.

The Sweet 16 and Elite Eight are the following week between March 27 and 30. The Final Four is on April 5 with the championship on April 7. 

When does March Madness end?

March Madness concludes with the 2025 national championship game on Monday, April 7.

Where will March Madness be played?

The Final Four of the 2025 NCAA Tournament will be played at the Alamodome in San Antonio.

πŸ’° March Madness betting odds pages

πŸ‘‘ Best March Madness betting sites

Ready to place your March Madness bets? Check out the best March Madness betting promos from our best March Madness betting sites, as determined by our expert team at Sportsbook Review.

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