Skip to main content

March Madness Sweet 16 Schedule Today: 2025 NCAA Tournament Sweet 16 Game Info, Odds

Gary Pearson

Last Updated: March 28, 2025 7:53 AM EDT • 2 min 22 sec read.

March Madness Sweet 16 Odds & Schedule: 2025 NCAA Tournament Sweet 16 Game Info Today
Pictured: Duke Blue Devils forward Mason Gillis shoots against the Baylor Bears. Photo by Zachary Taft via Imagn Images.

There's no way around it: the first two rounds of March Madness were about as chalky as it gets. The following seeds advanced: All four No. 1 seeds, three No. 2 seeds, two No. 3 seeds, three No. 4 seeds, one No. 5 seed, two No. 6 seeds, and a No. 10 seed.  

Kudos to No. 10 Arkansas, the final double-digit domino to fall in the Sweet 16, which concludes tonight. The best thing about chalky tournaments is the elite head-to-head matchups in the latter rounds.

The 2025 March Madness Sweet 16 schedule and odds are full of the nation's best, including the March Madness odds favorite Duke Blue Devils. The schedule and NCAA Tournament Sweet 16 betting lines below, including game times and TV schedule, will crank the excitement dial.

We offer our best bets for each game with our March Madness Sweet 16 predictions.

🗓️ March Madness Sweet 16 schedule

Here is the remaining March Madness Sweet 16 schedule for today. Listed odds are from BetMGM.

DayMatchupTimeHow to watch
FridayNo. 2 Michigan State vs. No. 6 Mississippi7:09 p.m. ET CBS
FridayNo. 2 Tennessee vs. No. 3 Kentucky7:39 p.m. ETTBS/truTV
FridayNo. 1 Auburn vs. No. 5 Michigan 9:39 p.m. ETCBS
FridayNo. 1 Houston vs. No. 4 Purdue10:09 p.m. ET TBS/truTV

👉 See all of the college basketball odds from our best March Madness betting sites.

Sbr Ncaab Final Weekend Challenge Lobby

🏀 Sweet 16 odds & predictions for today 

Here are Friday's March Madness odds:

No. 2 Michigan State vs. No. 6 Ole Miss odds, 7:09 p.m. ET

No. 2 Tennessee vs. No. 3 Kentucky odds, 7:39 p.m. ET

No. 1 Auburn vs. No. 5 Michigan odds, 9:39 p.m. ET

No. 1 Houston vs. No. 4 Purdue odds, 10:09 p.m. ET

⏰ When is March Madness Sweet 16?

The 2025 NCAA Tournament Sweet 16 takes place today with four games. The early games start at 7:09 p.m. ET and 7:39 p.m. ET, while the later games start at 9:39 p.m. ET, and 10:09 p.m. ET. 

🧠 Sweet 16 expert picks

🆚 Sweet 16 game predictions

💰 March Madness betting odds pages

March Madness oddsMarch Madness MVP odds
Women's March Madness oddsMarch Madness MVP predictions
Final Four oddsMarch Madness prop bets

👑 Best March Madness betting sites

Ready to place your March Madness bets? Check out the best March Madness betting promos from the best March Madness betting sites, as determined by our expert team at Sportsbook Review.

(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.

Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission

Written By:
Gary Pearson
Gary Pearson has written professionally since 2010, focusing on sports betting since 2014. Before entering the sports betting space, he contributed to the Canadian Press, FanSided, the Hockey Writers, the Calgary Herald, and other publications. His work has also been featured in Sports Illustrated and Bleacher Report. Gary, who consumes sports like a blue whale devours plankton, has a penchant for writing predictions and analyses across several sports, including hockey, soccer, football, tennis, and more. He bets regularly, preferring single-game picks, props, and live betting. While there isn't a sport he has yet to dabble in, Gary prefers betting on soccer, hockey, and football. He studied at various post-secondary institutions, including the University of Calgary, SAIT Polytechnic, and Griffith University, located in Brisbane, Australia. Gary has a marketing degree and completed his bachelor's degree in journalism at Griffith University. He feels strongly that life experience is as essential as post-secondary education, helping formulate more accurate predictions and analyses. Gary believes that competing at a high level of amateur sports during his formative years helped him better understand an athlete's psyche and the nuances and complexities of a team's dynamic, both on and off the playing surface. He feels that knowledge is immeasurably important when offering his analytical expertise. He has lived on five continents and currently resides in Canada.