Michigan State vs. Bryant Prediction, Odds & Preview Tonight: Best Picks for NCAA Tournament First Round

Rocket Arena in Cleveland is where we expect the No. 2 seed Michigan State Spartans (27-6) to run roughshod over the No. 15 seed Bryant Bulldogs (23-11) in tonight's NCAA Tournament first round at 10 p.m. ET (TBS).
Here are our Michigan State vs. Bryant prediction, odds, and preview, part of our March Madness predictions, which expect a lopsided victory for the higher seed and a stress-free pass to the next phase of the South Region of the March Madness bracket.
🏀 Michigan State vs. Bryant prediction & picks today
Here are my best Michigan State vs. Bryant predictions for the first round of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:
✅ Against the spread pick: Michigan State -17.5 (-105 via FanDuel) vs. Bryant ⭐⭐⭐⭐⭐
🔥 Best player prop bet: Tre Holloman Over 10.5 points (-110 via BetMGM) ⭐⭐⭐⭐
🎯 Exact score prediction: Michigan State 93, Bryant 64 (+20000 via DraftKings)
👉 Want more picks? Check out our latest college basketball picks and the rest of our March Madness first-round predictions.
🤖 See our March Madness AI bracket predictions for every game through Monday, April 7
🔢 Michigan State vs. Bryant updated betting action
- We've seen a bit of sharp money on the favorite despite the massive spread in this one, as 60% of the betting handle at BetMGM is on Michigan State to cover
- The betting splits on the total are far more extreme; 70% of the handle is on the Under
- Despite the majority of the action coming on Michigan state to cover, this spread hasn't moved since going to -17.5 in the middle of the week
🏆 Best Michigan State vs. Bryant pick, player prop bet & score prediction
Our NEW college basketball player prop odds tool can help you find the best odds for any March Madness market across legal sportsbooks in your area!
✅ Michigan State to cover the spread: -17.5 ⭐⭐⭐⭐⭐
This massive spread is warranted. Although Michigan State lost by three to the Wisconsin Badgers in the Big Ten semifinals, they are among the March Madness odds contenders and one of the hottest teams entering the tournament.
They have won eight of their last nine, with seven of those wins over ranked opponents. Five of those seven wins were by double digits.
The Bulldogs were just 6-9 in nonconference games this season, losing by 22 to the St. John’s Red Storm and 46 to the Grand Canyon Lopes. Those performances against tournament teams make it hard to see how they will compete.
The Bulldogs average over 80 points per game, but I would be shocked if they came anywhere near that total against the Spartans’ 37th-ranked scoring defense. The Spartans are allowing just 67.2 points per game, and they average more than 77 per, so I expect this to be a blowout from the opening tip.
📊 Best odds: -105 via FanDuel (bet $10 to win $9.52)
🔥 Tre Holloman Over 10.5 points ⭐⭐⭐⭐
It’s hard to predict which Spartan will have a great game on any given day, as they’re a team with numerous players who can score. The team’s leading scorer, Jaden Akins, is averaging just 12.7 points per game, and 10 players are averaging at least 4.5. But in a game that should get out of hand, I’m confident most players will go over their season averages, especially Holloman.
Holloman averages only 9.0 points per game this season, but he’s been excellent down the stretch. He scored 10 in the Big Ten final, and he’s now scored in double figures in three of his last four. He scored 20 against the Michigan Wolverines in one of those games.
I like Holloman more than Akins or Jase Richardson because his total is because his total is the lowest. The Bulldogs give up 74.5 points per game, so I think all three players will hit the Over. Holloman doesn’t have to do much more than usual to get to his number, and the price at BetMGM is the most appealing of our best sports betting apps.
📊 Best odds: -110 via BetMGM (bet $10 to win $9.09)
🎯 Score prediction: Michigan State 93, Bryant 64
This should be one of the most lopsided games of the first round. The Bulldogs are allowing over 74 points per game, and they played 19 games against the America East. They played two tournament teams, with both scoring at least 99 against their porous defense.
The Bulldogs will want to get out and run, but the Spartans’ defense won’t let them, frustrating what is usually a high-powered offense, resulting in them scoring nearly 20 points fewer than usual. The only reason the Spartans won’t hit 100 is because they will pull their key players early.
📊 Best odds: +20000 via DraftKings (bet $10 to win $2,000)
🤖 Michigan State vs. Bryant AI prediction
For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for Michigan State vs. Bryant. Our AI prediction projects a final score of Michigan State 85, Bryant 65.
🖥️ AI score prediction: Michigan State 85, Bryant 65
- Bryant has struggled in matchups against Big Ten teams, having lost their last nine games against such opponents.
- Bryant’s scoring has been more inconsistent against higher-level teams, and they’ll struggle to maintain a high level of offense against Michigan State’s defense.
- Michigan State's defense is a strong factor. They are known for their ability to lock down opponents, which will be crucial against a less-experienced team like Bryant.
🤔 Betting takeaway: ChatGPT's AI prediction would mean Michigan State covering the spread (-17.5) and a total of Under 152.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.
📊 Live Michigan State vs. Bryant odds
Follow the latest live March Madness college basketball odds and real-time NCAA Tournament scores for the first round.
Latest Michigan State vs. Bryant odds
Our updated Michigan State vs. Bryant odds are via BetMGM.
Spread
- The Spartans are 17.5-point betting favorites juiced at -110, carrying an implied probability of 52.38%
- The Bulldogs (+17.5) are juiced at -110, also implying a 52.38% probability.
Total
- The Michigan State vs. Bryant betting total is at 150.5 points. The Over and Under are at the -110 standard juice.
Moneyline
- Michigan State is the -2500 favorites (96.15%), and Bryant is the +1200 underdog (7.69%).
🔢 Michigan State vs. Bryant opening odds
- Spread: Michigan State -17.5 (-110) | Bryant +17.5 (-110)
- Moneyline: Michigan State -3000 | Bryant +1200
- Over/Under: Over 150.5 (-110) | Under 150.5 (-110)
📅 Check out the full March Madness first-round schedule and opening odds.
🔮 South Region expert picks
Here are our experts' best predictions for every game in the South Region
- South Region betting preview
- Auburn vs. Alabama State prediction
- Louisville vs. Creighton prediction
- UC San Diego vs. Michigan prediction
- Texas A&M vs. Yale prediction
- Ole Miss vs. North Carolina prediction
- Iowa State vs. Lipscomb prediction
- New Mexico vs. Marquette prediction
- Michigan State vs. Bryant
📺 How to watch Michigan State vs. Bryant: NCAA Tournament 1st round
📅 Date: Friday, March 21
🕗 Time: 10 p.m. ET
📍 Location: Rocket Arena (Cleveland)
📺 TV: TBS
💻 Streaming: March Madness Live
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