NC State vs. LSU Prediction Tonight: Women's Sweet 16 Best Bets, Odds & Preview

The No. 2 seed takes on the No. 3 seed in tonight's NCAA Tournament Sweet 16 game between the NC State Wolfpack (28-6) and the LSU Tigers (30-5). Tipoff from Spokane Arena in Spokane, Wash., is set for 7:30 p.m. ET (ESPN).
Our NC State vs. LSU prediction, odds, and preview - part of our women's March Madness predictions - expect a tightly contested matchup. The Tigers are 3.5-point betting favorites to advance in the Spokane 1 Region of the women's March Madness bracket. Which side will keep dancing?
🏀 NC State vs. LSU prediction & picks tonight
Here are my best NC State vs. LSU predictions for the Sweet 16 of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:
✅ Against the spread pick: NC State +3.5 (-110 via BetMGM) vs. LSU ⭐⭐⭐⭐
🔥 Best player prop bet: Aneesah Morrow Under 20.5 points (-114 via FanDuel) ⭐⭐⭐⭐
🎯 Exact score prediction: NC State 70, LSU 69 (+19000 via DraftKings)
👉 Want more March Madness action? Check out the rest of our college basketball picks for both the men's and women's NCAA tournament.
🏆 Best NC State vs. LSU pick, player prop bet & score prediction
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✅ NC State to cover the spread: +3.5 ⭐⭐⭐⭐
When these two teams met earlier this season, the Tigers won 82-65 by shooting 52.7% from the field, 50% from 3-point range, and outrebounding the Wolfpack 44-24. In that game, the Wolfpack shot just 35.9% from the field, and though they won the turnover battle 21-13, they never had a chance to win for the final 30 minutes of the game.
Despite how dominant the Tigers were, the spread for this game is only 3.5 points. This feels like a trap from oddsmakers at our best sports betting sites. The Wolfpack are 17-2 in their last 19 games, so they’re one of the hottest teams in the country. However, the head-to-head matchup is likely to resonate more with bettors.
All that said, I’m siding with the oddsmakers in this one and backing the Wolfpack to keep this close and possibly win. Their final game before the NCAA Tournament was a 76-62 loss to the Duke Blue Devils, but they also beat Duke earlier this season 89-83. Their only other loss during the last two months was a one-point defeat to the North Carolina Tar Heels. They got revenge in the ACC Tournament, winning by 11.
NC State is also the third-most bet team to win on the moneyline at BetMGM during the Sweet 16.
📊 Best odds: -110 via BetMGM ($10 to win $9.09)
🔥 Aneesah Morrow Under 20.5 points ⭐⭐⭐⭐
Morrow exploded for 26 points in the Round of 32 against the Florida State Seminoles. It was her third time scoring at least 25 points in her last five games.
Morrow is averaging 18.5 points per game. Though she has been great in her last five contests, she’s actually scored fewer than 20 points in 10 of her last 14 games. In the Tigers’ dominant win over the Wolfpack in November, Morrow scored 20 points in 39 minutes.
The Wolfpack are allowing an average of 64.6 points per game, which ranks just 186th in the nation. However, they’ve held three of their last four opponents to 55 or fewer points, and even if they allow 65 on Friday, that will be significantly less than they allowed the first time they played the Tigers. That would spell trouble for Morrow, especially with this number set two points higher than her season average.
📊 Best odds: -114 via FanDuel ($10 to win $8.77)
🎯 Score prediction: NC State 70, LSU 69
This game is a toss-up. The Tigers started the season 20-0, but they’re just 10-5 since then. They’ve lost three of their last six games, and though they’ve blown out both of their NCAA Tournament foes, their performance against the SEC at the end of the season is worrisome.
The Wolfpack have been great down the stretch, but they were also dominated by the Tigers earlier this season. Therefore, it would be irresponsible to completely write off the Tigers. I’ll take the Wolfpack to narrowly pull off the upset, but I won’t be surprised if either team advances.
📊 Best odds: +19000 via DraftKings ($10 to win $1,900)
🤖 NC State vs. LSU AI prediction
For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for NC State vs. LSU. Our AI prediction projects a final score of LSU 79, NC State 74.
🖥️ AI score prediction: LSU 79, NC State 74
- The Wolfpack (28-6) are making their sixth Sweet 16 appearance in the last seven NCAA Tournaments.
- Averaging 77 points per game, the Wolfpack outscore opponents by 12.4 points on average.
- In their earlier encounter this season, the Tigers defeated the Wolfpack 82-65, with a notable 20-rebound advantage.
🤔 Betting takeaway: ChatGPT's AI prediction would mean LSU covering the spread (-3.5) and a total of Under 153.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.
📊 Live NC State vs. LSU odds
Follow the latest women's March Madness odds for the NCAA Tournament.
🆕 NC State vs. LSU latest odds
LSU opened up as a 3.5-point betting favorite, and that's where Kim Mulkey's team remains in the hours leading up to tipoff tonight. The Tigers ended the season on a skid due to injuries, but our best live betting sites are now showing the fully healthy SEC squad the respect it deserves.
Flau'jae Johnson's presence back in the team has seen the public back LSU leading up to the Sweet 16 showdown. The Tigers moved from -162 to -185 on the moneyline, with the total staying put at O/U 153.5.
🔢 NC State vs. LSU opening odds
- Spread: NC State +3.5 (-110) | LSU -3.5 (-110)
- Moneyline: NC State +136 | LSU -162
- Over/Under: Over 153.5 (-110) | Under 153.5 (-110)
📺 How to watch NC State vs. LSU: Women's Sweet 16
📅 Date: Friday, March 28
🕗 Time: 7:30 p.m. ET
📍 Location: Spokane Arena (Spokane, Wash.)
📺 TV: ESPN
💻 Streaming: March Madness Live
🆚 Sweet 16 game predictions
- Duke vs. North Carolina prediction
- South Carolina vs. Maryland prediction
- NC State vs. LSU prediction
- UCLA vs. Ole Miss Prediction
💰 March Madness betting odds pages
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