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Purdue vs. High Point Prediction, Odds & Preview Today: March Madness First Round Best Bets
Pictured: Purdue Boilermakers guard Myles Colvin (5) evades a defender. Photo by Alex Martin/Journal and Courier / USA TODAY NETWORK via Imagn Images.

The No. 4 seed Purdue Boilermakers (22-11) open their tournament run today at 12:40 p.m. ET (truTV) against the No. 13 seed High Point Panthers (29-5) in the Midwest Region. Our Purdue vs. High Point predictions, odds, and preview has you covered for this first-round NCAA Tournament matchup with the Boilermakers as 8.5-point betting favorites at at Amica Mutual Pavilion in Providence, R.I.

As part of our best March Madness predictions, we’re looking for Kezza Giffa’s offensive output to stay around his season norm.

🏀 Purdue vs. High Point prediction & picks today

Here are my best Purdue vs. High Point predictions for the first round of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:

✅ Against the spread pick: High Point +8.5 (-118 via BetMGM) vs. Purdue ⭐⭐⭐⭐
🔥 Best player prop bet: Kezza Giffa Over 12.5 points (
-110 via FanDuel) ⭐⭐⭐⭐⭐
🎯 
Exact score prediction: High Point 79, Purdue 75

👉 Want more picks? Check out our latest college basketball picks and the rest of our March Madness first-round predictions.

🤖 See our March Madness AI bracket predictions for every game through Monday, April 7

🔢 Purdue vs. High Point updated betting action

  • 58% of bets are on High Point to cover (+7.5)
  • 55% of bets are on the Over
  • Purdue opened as 8.5-point betting favorites, which has since decreased to 7.5 points as of Thursday at 8:30 a.m. ET (BetMGM)

🏆 Best Purdue vs. High Point pick, player prop bet & score prediction

Our NEW college basketball player prop odds tool can help you find the best odds for any March Madness market across legal sportsbooks in your area!

✅ High Point to cover the spread: +8.5 ⭐⭐⭐⭐

High Point didn’t play a single Quad 1 game this season, but it can be carried by its explosive offense, with the Panthers averaging 81.7 points per game. If High Point can withstand the early minutes of this matchup without getting run off the floor by an opponent superior to anything it has seen so far, the Panthers could be in business.

They hold a distinct statistical edge in an area of struggle for the Boilermakers. High Point ranks 15th in the nation in two-point field goal percentage, an advantage over a Purdue team that ranks 348th out of 364 Division 1 teams in two-point defense.

Though High Point’s mediocre defense could be susceptible to Purdue’s seventh-ranked adjusted offensive efficiency in the country, the Panthers could stay competitive if they hold to their end of the bargain scoring the basketball in a defense-optional affair.

📊 Best odds: -118 via BetMGM ($10 to win $8.47)

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🔥 Kezza Giffa Over 12.5 points ⭐⭐⭐⭐⭐

We’re looking to target a scorer with a points prop a couple of notches lower than his season output in a game environment expected to be high-scoring, given the elevated total of 153.5 points.

High Point guard Kezza Giffa has averaged 14.8 points per game and has cleared 12.5 points in 10 of his past 13 contests. Given Purdue’s weakness defensively - the Boilermakers rank 240th in effective field goal defense - Giffa should be primed for a successful outing, even considering the step up in competition relative to the Panthers’ weak schedule.

FanDuel lists Giffa’s line at 12.5 points with -110 odds on Over, while BetMGM offers +100 odds on Over 13.5 points.

📊 Best odds: -110 via FanDuel ($10 to win $9.09)

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🎯 Score prediction: High Point 79, Purdue 75

In recent March Madness history, we’ve seen 13 seeds find success over 4 seeds, with three of the past four tournaments seeing at least one 13-over-4 upset. I’m going out on the limb that the Panthers can be the team to get it done in 2025. 

High Point’s adjusted offensive efficiency nearly rivals Purdue. When it comes to closing out competitive games, the Boilermakers rank 147th in free-throw percentage, several percentage points behind a Panthers team that ranks 47th in knocking down its freebies.

While both offenses can score, neither team plays at a pace fast enough to push our final score projection too far beyond the projected total of 153.5.

🤖 Purdue vs. High Point AI prediction

For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for Purdue vs. High Point. Our AI prediction projects a final score of Purdue 78, High Point 68.

🖥️ AI score prediction: Purdue 78, High Point 68

  • Purdue’s Size and Experience: The Boilermakers’ frontcourt dominance, led by their physical interior play, gives them a significant rebounding and scoring edge, making it tough for High Point to keep up.
  • Upset Potential: While High Point is on a 14-game winning streak and 13 seeds have a history of upsetting 4 seeds, Purdue’s superior strength of schedule and defensive efficiency make the upset unlikely.
  • Betting Trend Alert: Purdue’s recent struggles (losing six of their last nine) create some value on High Point against the spread, but Purdue’s overall talent and tournament experience should prevail.

🤔 Betting takeaway: ChatGPT's AI prediction would mean Purdue covering the spread (-8.5) and a total of Under 153.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.

🏀 Best March Madness odds, predictions & expert picks today

📊 Live Purdue vs. High Point odds

Follow the latest live March Madness college basketball odds and real-time NCAA Tournament scores for the first round.

Latest Purdue vs. High Point odds

Our updated Purdue vs. High Point odds are via BetMGM.

Spread

Purdue is an 8.5-point betting favorites ahead of tipoff. The Boilermakers held strong at the opening betting line, but High Point +8.5 is juiced to -115 odds.

Total

The Purdue-High Point betting total is at 154.5 points. There are equal -110 odds on either side of the Over/Under.

Moneyline

Purdue is a significant -385 moneyline favorite for the straight-up win. Those odds represent an 80% implied win probability.

🔢 Purdue vs. High Point opening odds

  • Spread: Purdue -8.5 (-110) | High Point +8.5 (-110)
  • Moneyline: Purdue -375 | High Point +300
  • Over/Under: Over 154.5 (-110) | Under 154.5 (-110)

📅 Check out the full March Madness first-round schedule and opening odds.

🔮 Midwest Region expert picks

📺 How to watch Purdue vs. High Point: NCAA Tournament first round

📅 Date: Thursday, March 20
🕗 Time: 12:40 p.m. ET
📍 Location: Amica Mutual Pavillion (Providence, R.I.)
📺 TV: truTV
💻 Streaming: March Madness Live, Sling TV

💰 March Madness betting odds pages

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