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UCLA vs. Ole Miss Prediction Tonight: Best Odds, Picks & Preview for Women's March Madness
Pictured: UCLA Bruins center Lauren Betts (51) celebrate scoring a basket with forward Kendall Dudley (22) in the NCAA Tournament. Photo by Robert Hanashiro / Imagn Images.

The No. 1 seed UCLA Bruins (32-2) look to continue their quest for an NCAA Tournament title when they take on the No. 5 seed Ole Miss Rebels (22-10) in the women's March Madness Sweet 16 tonight at 10 p.m. ET (ESPN) at Spokane Arena in Spokane, Wash.

The Bruins are 8.5-point betting favorites to advance in the Spokane 1 Region of the women's March Madness bracket, and we're riding with the top seeds in our UCLA vs. Ole Miss prediction, odds, and preview as part of our women's March Madness predictions.

🏀 UCLA vs. Ole Miss prediction & picks tonight

Here are my best UCLA vs. Ole Miss predictions for the Sweet 16 of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:

✅ Against the spread pick: UCLA -8.5 (-105 via DraftKings) vs. Ole Miss ⭐⭐⭐⭐
🔥 Best player prop bet: Lauren Betts Over 9.5 rebounds (
-114 via FanDuel) ⭐⭐⭐⭐
🎯 Exact score prediction: UCLA 76, Ole Miss 66 (+17000 via DraftKings)

👉 Want more March Madness action? Check out the rest of our college basketball picks for both the men's and women's NCAA tournament.

🏆 Best UCLA vs. Ole Miss pick, player prop bet & score prediction

Our NEW college basketball player prop odds tool can help you find the best odds for any March Madness market across legal sportsbooks in your area!

✅ UCLA to cover the spread: -8.5 ⭐⭐⭐⭐

The only team the Bruins have lost to this season is the USC Trojans. They've tallied 32 wins, with 28 coming through a nine-plus-point triumph. The school has notched two 17-plus-point victories to open the NCAA Tournament, yet the Bruins are only the 8.5-point favorite on Friday.

Though the Rebels are just 22-10, they’ve picked up some impressive wins and lost very close games against worthy opponents. They’ve played 12 games against ranked foes, and while Ole Miss is only 4-8 in those contests, the team also suffered a double-digit defeat in just three of those outings.

Despite how well the Rebels have been playing against the best competition, Lauren Betts and the Bruins are being undervalued entering this game. UCLA has been dominating nearly every opponent it's faced this season, including double-digit wins the majority of the time, often against teams better than the Rebels.

UCLA is the second-most bet team at BetMGM to cover the spread during the Sweet 16.

📊 Best odds: -105 via DraftKings ($10 to win $9.52)

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🔥 Lauren Betts Over 9.5 rebounds ⭐⭐⭐⭐

The Bruins boast the best rebounding margin in college basketball, and Betts is a significant reason why. She's averaging 9.7 rebounds per game, and Betts just pulled down 14 against the Richmond Spiders in the Round of 32.

While the Rebels rank 19th in rebounding margin, their margin is 5.3 less than the Bruins, which shows how amazing UCLA has been on the glass this season.

Betts has pulled down 10-plus rebounds in five of her last eight games. She likely would have reeled in more during the first round of the NCAA Tournament and the Big Ten semifinals had her minutes not been reduced with the Bruins ahead significantly.

The Bruins will win this game easily. But the Rebels will make it more competitive, which means Betts should play over 30 minutes, as she's done in most games this season. She'll hit this Over if that happens. After all, she’s pulled down 10-plus boards in six of her last eight games in which Betts has played 30-plus minutes.

📊 Best odds: -114 via FanDuel ($10 to win $8.77)

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🎯 Score prediction: UCLA 76, Ole Miss 66

The Bruins have scored 84 points in both of their NCAA Tournament games so far, but they’ll go Under that number on Friday. They’ve tallied 75 or fewer points during their last seven games against ranked opponents. UCLA will barely top that number on Friday against the inconsistent Rebels.

While the Rebels won’t actually threaten to win this game, they’ve played a lot of talented teams this season, and that experience will help them keep this affair close. They won’t come near their season average of 75.7 against this defense, but they’ll keep this game respectable.

📊 Best odds: +17000 via DraftKings ($10 to win $1,700)

🤖 UCLA vs. Ole Miss AI prediction

For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for UCLA vs. Ole Miss. Our AI prediction projects a final score of UCLA 72, Ole Miss 63.

🖥️ AI score prediction: UCLA 72, Ole Miss 63

  • The Rebels have made significant strides in recent years, reaching the Sweet 16 for the first time in over a decade. Their defense has been a cornerstone of the team's success, and they will rely on it heavily in this game.
  • The Bruins have been dominant during the tournament, including a decisive 84-67 victory over Richmond in the second round. Lauren Betts' performance has been particularly impressive, most notably a 30-point, 10-rebound game, marking the first time a Bruin has achieved such a feat in NCAA Tournament history.
  • While Ole Miss has demonstrated resilience and a strong defense, UCLA's depth, experience, and standout players like Betts position them as the likely winners in this matchup.

🤔 Betting takeaway: ChatGPT's AI prediction would mean UCLA covering the spread (-8.5) and a total of Over 133.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.

📊 Live UCLA vs. Ole Miss odds

Follow the latest women's March Madness odds for the NCAA Tournament.

🔢 UCLA vs. Ole Miss opening odds

  • Spread: UCLA -8.5 (-110) | Ole Miss +8.5 (-110)
  • Moneyline: UCLA -380 | Ole Miss +300
  • Over/Under: Over 133.5 (-110) | Under 133.5 (-110)

📺 How to watch UCLA vs. Ole Miss: Women's March Madness

📅 Date: Friday, March 28
🕗 Time: 10 p.m. ET
📍 Location: Spokane Arena (Spokane, Wash.)
📺 TV: ESPN
💻 StreamingMarch Madness Live

🆚 Sweet 16 game predictions

💰 March Madness betting odds pages

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