UConn vs. Oklahoma Prediction, Odds & Preview Today: Best Picks for Women's March Madness Sweet 16

The women's NCAA Tournament Sweet 16 rolls on today with No. 2 seed UConn (33-3) meeting No. 3 seed Oklahoma (27-7). Tipoff from Spokane Arena in Spokane, Wash., is at 5:30 p.m. ET (ESPN).
The Huskies are 15.5-point betting favorites to advance in the Spokane 4 Region of the women's March Madness bracket. As part of our March Madness predictions, we make our UConn vs. Oklahoma prediction, odds, and preview, explaining why the favorites won't have any trouble with the Sooners.
🏀 UConn vs. Oklahoma prediction & picks for today
Here are my best UConn vs. Oklahoma predictions for the Sweet 16 of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:
✅ Against the spread pick: UConn -15.5 (-110 via BetMGM) vs. Oklahoma ⭐⭐⭐⭐
🔥 Best player prop bet: Sarah Strong 20+ points (+172 via FanDuel) ⭐⭐⭐
🎯 Exact score prediction: UConn 86, Oklahoma 66 (+19000 via DraftKings)
👉 Want more March Madness action? Check out the rest of our college basketball picks for both the men's and women's NCAA tournament.
UConn vs. Oklahoma betting insights
- Bettors at BetMGM are aggressively backing the favorites, with 91% of the betting handle on the Huskies
- As for the total, bettors are taking on side (the Over) based on tickets, but the handle is nearly split, showing sharp money on the Under
- UConn remains a 15.5-point favorite just ahead of tipoff despite all the action
🏆 Best UConn vs. Oklahoma pick, player prop bet & score prediction
Our NEW college basketball player prop odds tool can help you find the best odds for any March Madness market across legal sportsbooks in your area!
✅ UConn to cover the spread: -15.5 ⭐⭐⭐⭐
The Sooners and Huskies dominated their first two opponents to reach the Sweet 16. The Huskies outscored the opposition 194-91, while the Sooners obliterated the Iowa Hawkeyes 96-62 in the second round. But can the high-scoring Sooners’ offense take care of business against the best scoring defense in America? It’s unlikely.
The Sooners are averaging 85.4 points per game, which ranks fifth in the nation. However, there is little doubt that the Huskies’ defense will have the edge in this game. The Sooners played the South Carolina Gamecocks twice this season, and they lost 101-60 and 93-75. The Gamecocks rank 33rd in scoring defense and the Sooners had no offensive answers against them.
But the biggest problem for the Sooners is they don’t defend well. They’re allowing 68.5 points per game, which ranks 272nd in the nation. Because of how both teams play, this is likely to be a shootout. The edge goes to the Huskies who are the more complete team. This is a large spread, but it is warranted.
📊 Best odds: -110 via BetMGM ($10 to win $9.09)
🔥 Sarah Strong 20+ points ⭐⭐⭐
The Huskies will score a lot of points in this game, so I’ll take a chance on one of their best scorers to go well over her season average for a great price. Strong is averaging 16.1 points per game this season, the second-most on the team behind only Paige Bueckers. She has scored at least 20 in two of her last four games and 35 in the NCAA Tournament.
Strong has played in all 36 games and scored at least 20 on 12 occasions. Essentially, she has a 33% chance of hitting this number, which is pretty much right in line with what these odds suggest. The price of +172 implies she has a 36.76% chance of scoring at least 20 points, and with how the Sooners play defense, that’s a fair implication.
Strong’s standard line is set at 16.5 points, but the Over carries a price of -128. That’s expensive for three points fewer than what we’re getting here. This is a bit of a risk, but in this matchup, it’s worth taking.
📊 Best odds: +172 via FanDuel ($10 to win $17.20)
🎯 Score prediction: UConn 86, Oklahoma 66
Bueckers, Strong, and the rest of the Huskies will have no trouble putting points on the board in this game. The Sooners like to play fast, and while that may work against Iowa, it won’t work against the Huskies.
The Huskies will give up nearly 15 more points than they do on average, but they’ll still hold the Sooners well below their usual total. A 20-point win seems very likely, and considering how both of these teams play, the final score could be even more lopsided.
📊 Best odds: +19000 via DraftKings ($10 to win $1,900)
🤖 UConn vs. Oklahoma AI prediction
For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for UConn vs. Oklahoma. Our AI prediction projects a final score of UConn 80, Oklahoma 68.
🖥️ AI score prediction: UConn 80, Oklahoma 68
- In the most recent matchup between these two teams on December 22, 2019, UConn defeated Oklahoma 97-53.
- The Huskies have reached the Final Four in 12 of the last 13 seasons.
- UConn boasts a deep roster with star players like Bueckers, one of the best players in women’s college basketball, and Azzi Fudd, who has been a key contributor all season.
🤔 Betting takeaway: ChatGPT's AI prediction would mean Oklahoma covering the spread (+15.5) and a total of Under 153.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.
📊 Live UConn vs. Oklahoma odds
Follow the latest women's March Madness odds for the NCAA Tournament.
🔢 UConn vs. Oklahoma opening odds
- Spread: UConn -14.5 (-110) | Oklahoma +14.5 (-110)
- Moneyline: UConn -1200 | Oklahoma +750
- Over/Under: Over 153.5 (-110) | Under 153.5 (-110)
UConn vs. Oklahoma line movement
All movement prior to tipoff via bet365.
Spread
This spread hasn't moved at bet365 since opening at 14.5 points, but we're seeing some of our sites with the best sportsbook promos lay a little additional juice on the favorites. UConn is trading at -120 to cover -14.5. At others, the Huskies are -15.5 betting favorites.
Total
Similar to the spread, this total hasn't moved since opening at 153.5.
Moneyline
However, the moneyline has seen some movement since opening. UConn is now trading at -1400 to win outright after opening at -1200. That means, if you're backing the underdogs, you're getting an additional $10 of potential profit for every $10 you wager with Oklahoma's odds at +850 vs. +750.
🆚 Sweet 16 game predictions
- TCU vs. Notre Dame prediction
- Texas vs. Tennessee prediction
- UConn vs. Oklahoma prediction
- USC vs. Kansas State prediction
📺 How to watch UConn vs. Oklahoma: Women's Sweet 16
📅 Date: Saturday, March 29
🕗 Time: 5:30 p.m. ET
📍 Location: Spokane Arena (Spokane, Wash.)
📺 TV: ESPN
💻 Streaming: March Madness Live
💰 March Madness betting odds pages
March Madness odds | March Madness MVP odds |
Women's March Madness odds | March Madness MVP predictions |
Final Four odds | March Madness prop bets |
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