USC vs. Mississippi State Prediction, Odds & Preview Tonight: Best Picks for Women's March Madness
The Mississippi State Bulldogs (22-11) have a gargantuan task on their hands when they face the No. 1 seed USC Trojans (29-3) in tonight's NCAA Tournament second round. The game tips off at 10 p.m. ET from Galen Center in Los Angeles (ESPN).
The Trojans are the 19.5-point betting favorites to easily advance to the Spokane 4 Region of the women's March Madness bracket, and we believe they'll do precisely that in our USC vs. Mississippi State prediction, odds, and preview, part of the women's March Madness predictions.
🏀 USC vs. Mississippi State prediction & picks for Monday
Here are my best USC vs. Mississippi State predictions for the second round of the NCAA Tournament; use our parlay calculator to get the best odds for any same-game parlay:
✅ Against the spread pick: USC -17.5 (-110 via BetMGM) vs. Mississippi State ⭐⭐⭐⭐
🔥 Best player prop bet: Jerkaila Jordan Under 4.5 rebounds (+116 via FanDuel) ⭐⭐⭐
🎯 Exact score prediction: USC 81, Mississippi State 58 (OFF)
👉 Want more picks? Check out our latest college basketball picks and the rest of our March Madness second-round predictions.
USC vs. Mississippi State updated betting action
Updated betting info via BetMGM
- USC moved from -17.5 to -19.5 in the lead-up to tipoff
- 78% of bets and 90% of the handle are on USC
- The total decreased from 147.5 to 146.5
- 82% of the bets and 90% of the handle are on the Under
🏆 Best USC vs. Mississippi State pick, player prop bet & score prediction
Our NEW college basketball player prop odds tool can help you find the best odds for any March Madness market across legal sportsbooks in your area!
✅ USC to cover the spread: -17.5 ⭐⭐⭐⭐
The Trojans are 11-1 against teams outside the Big Ten this season after their 71-25 win over the UNC Greensboro Spartans in the first round. They won nine of those games by at least 18 points, and they should be able to make it 10 of 13 tonight.
The Bulldogs haven’t lost a game by more than 12 points since Feb. 9, when they lost by 20 to the Alabama Crimson Tide. They’re 0-4 in their last four games against ranked opponents. Still, the Bulldogs lost by 27 points to the South Carolina Gamecocks and 22 points to the Kentucky Wildcats this season.
The Trojans’ balanced attack will prove too much for the middling team from the SEC. The Trojans are 10-1 in their last 11 games, with their only loss to the UCLA Bruins.
During that span, they beat numerous ranked teams by double digits, including the Ohio State Buckeyes by 21. This is a large spread, but I can't see the Bulldogs keeping it close against the women's March Madness odds contenders.
📊 Best odds: -110 via BetMGM ($10 to win $9.09)
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🔥 Jerkaila Jordan Under 4.5 rebounds ⭐⭐⭐
While Jordan is averaging 5.8 rebounds per game this season, she’s secured that number with inconsistent play on the glass. In the first round, she pulled down just three boards against the California Golden Bears, ending a streak of three consecutive games with at least six.
Jordan has 13 games with four or fewer rebounds this season, and she has pulled down four or fewer in five of her last nine. Tonight, she takes on a team with three players who average at least seven rebounds per game. The Trojans have the 15th-best rebounding margin in the country, and in this type of matchup, I don’t see how Jordan has success.
It would be nice to get this total at 5.5, but the Under is worth a play for this price. That said, this is still just a three-star play because we need Jordan to grab two fewer rebounds than she usually does. FanDuel offers the best odds of our top March Madness betting sites.
📊 Best odds: +116 via FanDuel ($10 to win $11.60)
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🎯 Score prediction: USC 81, Mississippi State 58
Both teams rank in the top 50 in the nation in points per game, but the Bulldogs will struggle against one of the country's best defenses. The Trojans should get right around their season average.
The Trojans allow just 58.8 points per game, so even though the Bulldogs are averaging 75.5 per contest, they will hold them in check and cruise to the Sweet 16. This exact score isn’t available at any of our best sportsbooks, but if exact score props become available before tipoff, you'll see a line of around +19000 or +20000.
📊 Best odds: OFF
🤖 USC vs. Mississippi State AI prediction
For entertainment purposes, we asked ChatGPT to analyze historical trends and live NCAA Tournament stats before predicting the winner and exact score for USC vs. Mississippi State. Our AI prediction projects a final score of Mississippi State 72, USC 64.
🖥️ AI score prediction: Mississippi State 72, USC 64
- The Trojans’ offense is solid but not as explosive as some other teams in the tournament. They focus on a balanced attack and opportunistic scoring.
- The Bulldogs have a well-balanced offense, averaging around 75 points per game. They rely on a mix of inside play and perimeter shooting.
- USC has been a consistent presence in the NCAA Tournament, particularly in recent years. While the Trojans haven’t won a championship, they’ve regularly made deep runs, including appearances in the Final Four and Elite Eight.
🤔 Betting takeaway: ChatGPT's AI prediction would mean Mississippi State covering the spread (+16.5) and a total of Under 147.5 points. ChatGPT is not a dedicated sports betting model, but it can identify data that March Madness bettors might overlook.
📊 Live USC vs. Mississippi State odds
Follow the latest live March Madness college basketball odds and real-time NCAA Tournament scores for the second round.
Latest USC vs. Mississippi State odds
Here are the latest odds for USC vs. Mississippi State from BetMGM ahead of tipoff:
Spread
USC is a 19.5-point betting favorite against Mississippi State. Both sides are juiced at -110.
Total
The USC vs. Mississippi State betting total sits at 145.5 ahead of tipoff. That Over/Under is juiced at -110 on both sides.
Moneyline
USC is a -5000 moneyline favorite with an implied win probability of 98.04% against Mississippi State.
🔢 USC vs. Mississippi State opening odds
- Spread: USC -16.5 (-110) | Mississippi State +16.5 (-110)
- Moneyline: USC -2400 | Mississippi State +1200
- Over/Under: Over 147.5 (-110) | Under 147.5 (-110)
📺 How to watch USC vs. Mississippi State: NCAA Tournament second round
📅 Date: Monday, March 24
🕗 Time: 10 p.m. ET
📍 Location: Galen Center (Los Angeles)
📺 TV: ESPN
💻 Streaming: March Madness Live
💰 March Madness betting odds pages
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