NFL Week 12 Best Bets: Predictions, Player Props & ATS Picks

Six NFL teams are on byes in Week 12 as the remaining 26 look to position themselves well before Thanksgiving.
- Only two teams are favored by 10-plus points in Week 12 after five games with double-digit favorites from Weeks 1-11
- The Cowboys are looking to avoid their sixth straight SU and ATS loss for the first time since 1988-89
Our NFL Week 12 best bets continue to ride the hot hand of a player among the Offensive Rookie of the Year odds favorites, and we try to hit on a five-star play with a six-point teaser parlay for the second consecutive week as part of our NFL Week 12 predictions.
Best NFL player props & ATS predictions for Week 12
NFL odds subject to change. Track the NFL scores for the latest line movement and matchup info.
- Brian Robinson Jr. to score 2+ touchdowns (+400 via DraftKings) vs. Cowboys ⭐⭐
- Bo Nix Over 213.5 passing yards (-110 via bet365) vs. Raiders ⭐⭐⭐⭐
- Teaser parlay: Dolphins -1 and Bears +9.5 (-125 via Caesars) ⭐⭐⭐⭐⭐
- Panthers team total Under 15.5 (-106 via FanDuel) vs. Chiefs ⭐⭐⭐⭐
Week 12 NFL odds & schedule
(Odds via BetMGM)
- Detroit Lions (-7.5) vs. Indianapolis Colts (+7.5), Sunday at 1 p.m. ET
- Tennessee Titans (+8) vs. Houston Texans (-8), Sunday at 1 p.m. ET
- New England Patriots (+7.5) vs. Miami Dolphins (-7.5), Sunday at 1 p.m. ET
- Minnesota Vikings (-3.5) vs. Chicago Bears (+3.5), Sunday at 1 p.m. ET
- Kansas City Chiefs (-11) vs. Carolina Panthers (+11), Sunday at 1 p.m. ET
- Tampa Bay Buccaneers (-5.5) vs. New York Giants (+5.5), Sunday at 1 p.m. ET
- Dallas Cowboys (+10) vs. Washington Commanders (-10), Sunday at 1 p.m. ET
- Denver Broncos (-6) vs. Las Vegas Raiders (+6), Sunday at 4:05 p.m. ET
- Arizona Cardinals (+1) vs. Seattle Seahawks (-1), Sunday at 4:25 p.m. ET
- San Francisco 49ers (+2) vs. Green Bay Packers (-2), Sunday at 4:25 p.m. ET
- Philadelphia Eagles (-3) vs. Los Angeles Rams (+3), Sunday at 8:20 p.m. ET
- Baltimore Ravens (-3) vs. Los Angeles Chargers (+3), Monday at 8:15 p.m. ET
NFL props for Week 12
NFL picks made Friday; odds subject to change. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!
Brian Robinson Jr. to score 2+ touchdowns ⭐⭐
Best odds: +400 via DraftKings | Implied probability: 20%
To call the Cowboys organization a disaster at this point may be an understatement. Dallas’ 3-7 record is tied for its worst start since 2020 - Mike McCarthy’s first season - and the team has been outscored by 102 points in the last five games with four losses by 24-plus points.
Dallas has allowed multiple rushing touchdowns to the same player in back-to-back weeks (Joe Mixon and Jalen Hurts) and three of the last five if we include David Montgomery’s two-touchdown performance in the Lions' 47-9 win in Week 6.
The Cowboys have allowed the third-most fantasy points per game to running backs over the last month and the second-most rushing yards per game this season.
Robinson has gone over 70 scrimmage yards in three consecutive games and has found the end zone at least once in five of his previous six.
Robinson’s anytime touchdown odds are juiced as high as -164 (carrying a 62.12% implied probability) at Caesars, so I am opting for the bigger payday with him to find the end zone twice.
One would net $40 in profits with a $10 winning wager at DraftKings’ +400 odds compared to the $26 with Caesars’ +260 odds for the same wager.
Bo Nix Over 213.5 passing yards ⭐⭐⭐⭐
Best odds: -110 via bet365 | Implied probability: 52.38%
Last week, I included Nix in my NFL best bets column, and he tied a Broncos rookie record with four touchdown passes - the first to do so since 1968 - and threw for a career-high 307 yards.
It’s a shame, then, that I advised none of that and opted for the Over on his 27.5 rushing yards instead (he finished with five).
Nix is the second rookie in NFL history with 200-plus passing yards and multiple touchdown passes in four straight home games. While this is a road game, he has a great matchup against a Raiders defense that has allowed 23 or more fantasy points to five quarterbacks this season and a top-10 performance in consecutive games.
This is a four-star play, as since Week 6, Nix has completed 69% of his passes, averaged 7.3 yards per attempt, posted an 11-2 TD-INT ratio, and has a 72 Total QBR. His completion percentage, TD-INT ratio, and Total QBR all rank in the top 10 in the NFL in that span.
Over backers are getting the best number and price at bet365. The rest of our best NFL prop betting sites have the Over of 213.5 juiced at least to -115, and Caesars has a slightly higher O/U at 214.5.
NFL game predictions for Week 12
Teaser parlay: Dolphins -1 and Bears +9.5 ⭐⭐⭐⭐⭐
Best odds: -125 via Caesars | Implied probability: 55.56%
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My first six-point teaser of the season cashed easily as a five-star play last week, so I am back with a second such play with an “if it ain’t broke, don’t fix it” attitude.
Since Tua Tagovailoa returned from his most recent concussion, Miami has righted the ship. The Dolphins have won consecutive games for the first time this season after a season-high 34-point performance, and Tagovailoa threw three touchdowns in a game for the first time since Week 8 of last season.
Who was his opponent the last time he threw for three touchdowns?
It was a home game against the same Patriots team he faces this weekend. By teasing the line down to -1, I am essentially backing the Dolphins to win outright.
The other leg of this teaser comes with optimism for a Bears squad coming off four straight losses. Two of those were on the last play, including a blocked field goal against the Packers and a Hail Mary gone wrong against the Commanders.
Caleb Williams showed tremendous growth in his first game under interim offensive coordinator Thomas Brown last week. After completing 61% of his passes and averaging 2.90 seconds to throw through the first nine games, Williams completed 74% of his passes and averaged 2.42 seconds to throw - his shortest in a game this season.
I am making this wager at Caesars, as it is the only shop offering Miami -7 (instead of -7.5) and Chicago +3.5 at the standard -110 juice.
Panthers team total Under 15.5 ⭐⭐⭐⭐
Best odds: -106 via FanDuel | Implied probability: 51.46%
The Bills gashed the Chiefs' defense last week, as Kansas City allowed 30 points in a game for the first time since Week 4 of 2022.
Over the last three seasons, the Chiefs’ 30 points allowed in Week 11 ranked second-worst, their zero sacks were the worst, the 60% third-down conversion rate allowed was second-worst, and their 24 Efficiency rating was third-worst.
The good news for Chiefs fans is that Bryce Young is nowhere near as talented as Josh Allen, who is the NFL MVP odds favorite. I do not expect a Panthers team that has scored 16-plus points in just half of its 10 games to light up the scoreboard against an angry Kansas City defense.
DraftKings offers -110 odds for the same number, while bet365 is juiced as high as -150 to back the team total Under 16.5. Thus, the best value is at FanDuel, where a $10 winning wager would pay out $19.43.
NFL betting odds pages
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- bet365 Bonus Code: SBRBONUS | Read our bet365 Review
- FanDuel Promo Code | Read our FanDuel Review
- DraftKings Promo Code | Read our DraftKings Review
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