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There's NFL football taking place on Thursday, Friday, Sunday, and Monday of this week as we round up our betting experts' top NFL predictions for Week 12 based on the odds from our best NFL betting sites.

After the annual NFL Thursday tripleheader, we have the first-ever Black Friday game on tap, followed by a shorter but intriguing Sunday slate. Key matchups on Sunday include the Jacksonville Jaguars visiting the Houston Texans in a crucial AFC South showdown and the Buffalo Bills facing off against the Philadelphia Eagles.

Be sure to scour the Super Bowl odds ahead of the action in order to get the best price on any lingering long shots.

Check out our best NFL predictions for Week 12 based on the top NFL Week 12 odds and betting lines.  

NFL picks and predictions for Week 12

NFL predictions Week 12: Monday Night Football

Bears +3.5 vs. Vikings pick: (-115 via Caesars) ⭐⭐⭐⭐

Bears-Vikings prediction made by Phil Wood.

NFL expert picks Week 12

NFL betting odds pages

Check out our best NFL betting sites:

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