NFL Week 10 Predictions 2024: Picks & Odds for Marquee Games

C Jackson Cowart

Last Updated: November 5, 2024 7:00 AM EST • 3 min 59 sec read. Twitter link Google News Link

Los Angeles Rams quarterback Matthew Stafford waits for a timeout as we offer our NFL Week 10 predictions. — Los Angeles Rams quarterback Matthew Stafford (9) waits for a timeout. Photo by Joe Nicholson / Imagn Images.

After an eventful first half of the NFL regular season, the second half begins on Thursday Night Football as we offer our NFL Week 10 odds and predictions.

The week kicks off with the Baltimore Ravens hosting the Cincinnati Bengals as Thursday Night Football odds favorites in a rematch of these teams' thrilling 41-38 duel that went Baltimore's way in Week 5.

Sunday's 12-pack of games begins at 9:30 a.m. ET with the New York Giants and Carolina Panthers facing off in Munich, while the day ends with a heavyweight clash by the Sunday Night Football odds between the Detroit Lions and Houston Texans.

Finally, the Los Angeles Rams host the Miami Dolphins as slim favorites by the Monday Night Football odds in a matchup between two teams with dwindling hopes in the latest Super Bowl odds.

NFL picks & predictions Week 10

Bengals vs. Ravens early picks (TNF)

Bengals vs. Ravens prediction
Bengals vs. Ravens player props
Bengals vs. Ravens parlay
Joe Burrow player props
Lamar Jackson player props
TNF anytime touchdown scorer predictions
TNF first touchdown scorer predictions

Giants vs. Panthers early picks (Munich)

Giants vs. Panthers prediction
Giants vs. Panthers player props

Bills vs. Colts player props
Broncos vs. Chiefs player props
49ers vs. Buccaneers player props
Eagles vs. Cowboys prediction

Eagles vs. Cowboys player props

Lions vs. Texans early picks (SNF)

LIons vs. Texans prediction
Lions vs. Texans player props
Lions vs. Texans parlay
Jared Goff player props
C.J. Stroud player props
SNF first touchdown scorer predictions

Dolphins vs. Rams early picks (MNF)

Dolphins vs. Rams prediction
Dolphins vs. Rams player props

Don't miss the rest of our Week 10 NFL picks. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

NFL odds & predictions for Thursday Night Football

NFL odds via BetMGM and subject to change. Follow the latest NFL scores for line history and matchup info.

Bengals vs. Ravens odds

Cincinnati Bengals defensive end Sam Hubbard pushes Baltimore Ravens quarterback Lamar Jackson as we examine the NFL Week 10 predictions. — Cincinnati Bengals defensive end Sam Hubbard pushes Baltimore Ravens quarterback Lamar Jackson out of bounds. Photo by Cara Owsley / The Enquirer via Imagn Images.

When: Thursday, Nov. 7 - 8:15 p.m. ET
Where: M&T Bank Stadium (Baltimore)
How to watch: Prime Video
Moneyline: Bengals +220 | Ravens -275
Spread: Bengals +6.5 (-120) | Ravens -6.5 (-110)
Total: 52.5 (-110/-110)

NFL odds & predictions for Sunday

Giants vs. Panthers odds

New York Giants quarterback Daniel Jones passes the ball as we offer our NFL Week 10 predictions. — New York Giants quarterback Daniel Jones passes the ball. Photo by Steven Bisig / Imagn Images.

When: Sunday, Nov. 10 - 9:30 a.m. ET
Where: Allianz Arena (Munich)
How to watch: NFL Network
Moneyline: Giants -225 | Panthers +180
Spread: Giants -4.5 (-110) | Panthhers +4.5 (-110)
Total: 41.5 (-110/-110)

49ers vs. Buccaneers odds

When: Sunday, Nov. 10 - 1 p.m. ET
Where: Raymond James Stadium (Tampa, Fla.)
How to watch: FOX
Moneyline: 49ers -300 | Buccaneers +240
Spread: 49ers -6.5 (-110) | Buccaneers +6.5 (-110)
Total: 48 (-110/-110)

Broncos vs. Chiefs odds

When: Sunday, Nov. 10 - 1 p.m. ET
Where: GEHA Field at Arrowhead Stadium (Kansas City, Mo.)
How to watch: CBS
Moneyline: Broncos +350 | Chiefs -450
Spread: Broncos +9.5 (-110) | Chiefs -9.5 (-110)
Total: 42 (-110/-110)

Patriots vs. Bears odds

When: Sunday, Nov. 10 - 1 p.m. ET
Where: Soldier Field (Chicago)
How to watch: FOX
Moneyline: Patriots +260 | Bears -350
Spread: Patriots +6.5 (-110) | Bears -6.5 (-110)
Total: 39.5 (-110/-110)

Falcons vs. Saints odds

When: Sunday, Nov. 10 - 1 p.m. ET
Where: Caesars Superdome (New Orleans)
How to watch: FOX
Moneyline: Falcons -175 | Saints +145
Spread: Falcons -3.5 (-105) | Saints +3.5 (-115)
Total: 46.5 (-110/-110)

Steelers vs. Commanders odds

When: Sunday, Nov. 10 - 1 p.m. ET
Where: Northwest Stadium (Landover, Md.)
How to watch: CBS
Moneyline: Steelers +120 | Commanders -145
Spread: Steelers +2.5 (-105) | Commanders -2.5 (-115)
Total: 45.5 (-110/-110)

Bills vs. Colts odds

When: Sunday, Nov. 10 - 1 p.m. ET
Where: Lucas Oil Stadium (Indianapolis)
How to watch: CBS
Moneyline: Bills -210 | Colts +170
Spread: Bills -4 (-110) | Colts +4 (-110)
Total: 47 (-110/-110)

Vikings vs. Jaguars odds

When: Sunday, Nov. 10 - 1 p.m. ET
Where: EverBank Stadium (Jacksonville, Fla.)
How to watch: FOX
Moneyline: Vikings -210 | Jaguars +170
Spread: Vikings -4 (-110) | Jaguars +4 (-110)
Total: 46 (-110/-110)

Titans vs. Chargers odds

Los Angeles Chargers quarterback Justin Herbert prepares to pass as we offer our NFL Week 10 predictions. — Los Angeles Chargers quarterback Justin Herbert prepares to pass. Photo by Ron Chenoy / Imagn Images.

When: Sunday, Nov. 10 - 4:05 p.m. ET
Where: SoFi Stadium (Inglewood, Calif.)
How to watch: FOX
Moneyline: Titans +310 | Chargers -400
Spread: Titans +7.5 (-110) | Chargers -7.5 (-120)
Total: 38 (-110/-110)

Eagles vs. Cowboys odds

When: Sunday, Nov. 10 - 4:25 p.m. ET
Where: AT&T Stadium (Arlington, Texas)
How to watch: CBS
Moneyline: Eagles -375 | Cowboys +300
Spread: Eagles -7.5 (-105) | Cowboys +7.5 (-115)
Total: 41.5 (-110/-110)

Jets vs. Cardinals odds

When: Sunday, Nov. 10 - 4:25 p.m. ET
Where: State Farm Stadium (Glendale, Ariz.)
How to watch: CBS
Moneyline: Jets +100 | Cardinals -120
Spread: Jets +1 (-110) | Cardinals -1 (-110)
Total: 46 (-110/-110)

NFL odds & predictions for Sunday Night Football

Lions vs. Texans odds

Detroit Lions quarterback Jared Goff makes a pass as we offer our NFL Week 10 predictions. — Detroit Lions quarterback Jared Goff makes a pass against the Tennessee Titans. Photo by Junfu Han / USA Today Network via Imagn Images.

When: Sunday, Nov. 10 - 8:20 p.m. ET
Where: NRG Stadium (Houston, Texas)
How to watch: NBC
Moneyline: Lions -165 | Texans +140
Spread: Lions -3 (-115) | Texans +3 (-105)
Total: 49 (-110/-110)

NFL odds & predictions for Monday Night Football

Dolphins vs. Rams odds

Miami Dolphins running back Raheem Mostert and quarterback Tua Tagovailoa celebrate as we offer our NFL Week 10 predictions. — Miami Dolphins running back Raheem Mostert celebrates with quarterback Tua Tagovailoa after scoring a touchdown. Photo by Sam Navarro via Imagn Images.

When: Monday, Nov. 11 - 8:15 p.m. ET
Where: SoFi Stadium (Inglewood, Calif.)
How to watch: ESPN
Moneyline: Dolphins +110 | Rams -135
Spread: Dolphins +2.5 (-110) | Rams -2.5 (-110)
Total: 50.5 (-110/-110)

NFL picks roundup: Week 10

NFL Week 10 picks against the spread
NFL Week 10 upset picks
NFL Week 10 player props
NFL Week 10 anytime touchdown scorer predictions
NFL Week 10 touchdown parlay

NFL betting odds pages

Super Bowl Odds	NFL MVP Odds	NFL Offensive Player of the Year Odds
NFL Defensive Player of the Year Odds	NFL Offensive Rookie of the Year Odds	NFL Defensive Rookie of the Year Odds
NFL Coach of the Year Odds	NFL Comeback Player of the Year Odds	NFL Win Totals Odds
NFL Playoff Odds	NFL Draft Odds

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Written By:
C Jackson Cowart

C Jackson Cowart is a publishing editor and lead writer for Sportsbook Review. An award-winning writer, reporter, and editor with a decade of sports media experience, "C-Jax" has worked with ESPN, Forbes, theScore, and various daily newspapers before joining the Sportsbook Review team. He's a proud graduate of the University of North Carolina, where he served as a beat writer for the Tar Heels' championship run through the NCAA men's basketball tournament in 2017. Jackson has spent the last five years covering sports betting as a predictive analyst, features writer, and industry reporter. Since joining the team in 2023, he's played a key role in Sportsbook Review's coverage of the Super Bowl, March Madness, and NBA playoffs while serving as the lead writer for the growing WNBA and NASCAR betting scenes. Though he's cashed some big bets over the years -- including Lamar Jackson to win MVP (twice) -- he's still haunted by enough second-place bet slips to wallpaper his home office. While Jackson is a committed "process over results" bettor with a keen eye for advanced stats and subtle bias in futures markets, he also embraces sports betting as a vehicle for entertainment and personal investment. He's written about everything from hot dogs to groundhogs and still hasn't forgiven his "inside source" for a sabotaged bet on the Gatorade color in Super Bowl LV.