Oilers vs. Panthers Predictions Tonight: Stanley Cup Game 6 Odds & Best Bet

The Florida Panthers are one win away from securing their second consecutive Stanley Cup. We examine whether they can make it happen at home in Game 6.
Oilers vs. Panthers Predictions
Pictured: Florida Panthers goaltender Sergei Bobrovsky guards his net against Edmonton Oilers right wing Corey Perry. Photo by Sergei Belski via Imagn Images.

The Edmonton Oilers are in must-win territory heading into Game 6 of the Stanley Cup Final tonight, with the Florida Panthers just one victory away from repeating as champions.

Despite oddsmakers favoring the home team across our best sports betting sites, our Oilers vs. Panthers predictions expect Edmonton to bounce back in this do-or-die showdown. Puck drop is set for 8 p.m. ET from Amerant Bank Arena (TNT) in Sunrise, Fla.

📈 Oilers vs. Panthers betting insights

According to BetMGM, 45% of bets and 73% of the money are on the Panthers' moneyline tonight, while 74% of bets and 75% of the money are on the Over. Just 28% of the money is on the Oilers +1.5.  

🔮 Oilers vs. Panthers prediction & picks for Game 6 tonight

🔎 Our NEW NHL player prop odds tool can help you find the best odds for your NHL picks across legal sportsbooks in your area!

✅ Who will win Oilers vs. Panthers: Oilers (+120 via bet365) ⭐⭐⭐
✅ Best prop bet: Under 6.5 goals (-120 via bet365) ⭐⭐⭐

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💰 Panthers vs. Oilers best bet

Here is my best bet for Game 6 of the 2025 Stanley Cup Final:

🚨 Oilers ML 

  • Best odds: +120 via bet365 (bet $10 to win $12 profit)
  • Implied win probability: 45.45%

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The Oilers are officially out of Mulligans, down to the last out. For the fourth time in five games, Kris Knoblauch's team allowed the opening goal. This time, however, the Panthers weren't in a giving mood, shutting up shop and taking Game 5 comfortably.

Teams that win Game 5 of the Stanley Cup Final hoist the Holy Grail 73% of the time, making the Oilers' behemoth task increasingly unlikely. However, the Oilers have overcome adversity several times in these playoffs, so if there's any team that can drag the Panthers to a decisive Game 7, it's them. I back one of their feisty veterans to give his all in my Oilers vs. Panthers player props.

I backed the Oilers since the start of the season, and I'm not about to waver. The Panthers are 5-4 at home, which should lift an Oilers crew that overcame a 3-0 first-period deficit when they last played at Amerant Bank Arena.

Another insipid start, however, will likely lead to the Panthers becoming back-to-back Stanley Cup winners, placing even more importance on bagging the opener.

Most of our best NHL betting sites have the Oilers pegged as +120 underdogs.

🏒 Panthers vs. Oilers odds tonight

Here are the live odds for Oilers vs. Panthers in Game 6. See the latest NHL odds for the Stanley Cup from our best NHL betting sites.

Odds analysis

After picking up a comfortable road win in Edmonton, bettors are backing the Panthers on home ice to get the job done tonight. Early betting shows 60% of the wagers on the home side, with the Panthers opening at -140 on the moneyline and trading closer as high as -155 on game day.

Despite a majority (69%) of tickets coming in on the Over, the odds are shading to the Under a little. The Under 6.5 opened at -115 but is now trading closer to -120. Despite bettors seemingly backing plenty of goals, sportsbooks seem to be preparing for a tighter defensive game.

💵 Best Stanley Cup betting sites

Want to bet on Panthers vs. Oilers in Game 6? Here are the best NHL betting sites and best sportsbook promos for the 2025 Stanley Cup Final:

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Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.