Stanley Cup Odds & Predictions Today: Best NHL Playoff Expert Picks for Tuesday, April 22

Thrilling doesn't do Monday's action justice as the NHL playoffs put on a spectacle to behold, featuring more goals than celebrities in Los Angeles, a pair of instant overtime classics, and a quintessential Winnipeg Jets defensive masterclass.  

It's on to Day 4 of the NHL playoffs, and we've got you covered as we provide the Stanley Cup odds and predictions today, offering expert picks and live betting tips for all four Tuesday contests. 

👉 For more any roster changes, check out our first round Injury update

🏆 Live Stanley Cup odds & prediction to win NHL playoffs

Stanley Cup odds via our best NHL betting sites. Updated in real time.

Four teams in the storied history of the NHL playoffs have overturned a four-goal deficit and prevailed. The Edmonton Oilers were on track to become the fifth before a Mighty Ducks-esque knuckle puck ended the quest in the most devastating fashion.

Still, the Oilers have a platform to springboard from after getting to Darcy Kuemper, who allowed five goals at home for the first time all season. 

He allowed five goals on 16 shots in the final 20:06. 

The Montreal Canadiens were a shot away from capping off a two-goal comeback but were thwarted by Alex Ovechkin's first-ever playoffs overtime winner. The year of Ovechkin continues, with the Great 8 ruining another of my exact score predictions. 

The Dallas Stars evened the series with my bet to win the Stanley Cup, the Colorado Avalanche, thanks to a heroic effort from the collective. While Dallas will be thrilled with the effort, it will be hard trudging in the Mile High City.

And what else can be said about Winnipeg's defensive mastery after allowing a paltry 1.57 expected goals to one of the hottest road teams down the stretch? 

💰 Best bet to win Stanley Cup: Colorado Avalanche (+750 via FanDuel)

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🏒 NHL playoff predictions & best bets for today Tuesday, April 22

Here are our best NHL predictions today for the 2025 Stanley Cup Playoffs, including our expert picks and full-game previews for every matchup. Odds courtesy of BetMGM; subject to change.

🚨 Devils vs. Hurricanes prediction, odds & expert picks

📍 Puck drop: 6 p.m. ET | 📺 TV: ESPN
📊 Odds: Devils (+220) | [Hurricanes (-275) | O/U 5.5

Here's why Connor Cooper is picking the Hurricanes to win by at least two goals. 

"The recent history between these teams doesn’t suggest that things will be any different when the series resumes Tuesday night. Although New Jersey split its four meetings with Carolina this season, Lenovo Center has been a house of horrors for the Devils for years. New Jersey has won just one of its last 13 visits, managing two goals or less in each of the last eight. Making things worse, the Devils could be without defenseman Brenden Dillon and/or forward Cody Glass on Tuesday after both left the series opener with injuries."

👉 Check out our full Devils vs. Hurricanes prediction for expert analysis, betting picks, and our favorite prop bets.

🚨 Senators vs. Maple Leafs prediction, odds & expert picks

📍 Puck drop: 7:30 p.m. ET | 📺 TV: ESPN2
📊 Odds: Senators (+155) | Maple Leafs (-185) | O/U 5.5

Here's why Gary Pearson is picking Under 5.5 goals.

"Anthony Stolarz has allowed two goals in his last three starts. Since losing 4-2 to Ottawa on March 15, Stolarz is 9-0-0. In the final eight games of the regular season, he posted three shutouts, had a .950 save percentage, and a 1.37 goals-against average.

If the Maple Leafs win, it will be because of Stolarz. Ullmark must be better for the Sens after finishing Game 1 with -2.1 goals saved above expected. That said, his team left him out to dry by their continual march to the penalty box."

👉 Check out our full Senators vs. Maple Leafs prediction for expert analysis, betting picks, and our favorite prop bets.

🚨 Panthers vs. Lightning prediction, odds & expert picks

📍 Puck drop: 8:30 p.m. ET | 📺 TV: TBS 
📊 Odds: Panthers (-105) | Lightning (-115) | O/U 5.5

Here's why Gary Pearson is picking the Lightning on the moneyline. 

"The Lightning enter the playoffs in markedly better form than their Sunshine State adversaries. While confidence won't be an issue for the defending Cup champions, the Panthers stumbled into the postseason and should struggle to overcome a healthy, in-form Lightning team.

The Panthers were tied for the second-worst road record (3-8-1) and scored the fewest goals per game (1.83) in enemy rinks since the 4 Nations break."

👉 Check out our full Panthers vs. Lightning prediction for expert analysis, betting picks, and our favorite prop bets.

🚨 Wild vs. Golden Knights prediction, odds & expert picks

📍 Puck drop: 11 p.m. ET | 📺 TV: ESPN
📊 Odds: Panthers (-105) | Lightning (-115) | O/U 5.5

Here's why Connor Cooper is expecting a low-scoring affair and taking Under 5.5 goals.

"The Wild have also struggled to generate much offense in recent meetings with the Golden Knights, potting just nine goals in the last six matchups against Vegas. Meanwhile, two of the Golden Knights’ four goals in Game 1 came on the powerplay - including Howden’s second of the night into an empty net.

Three of the last five games between these teams featured fewer than six goals, and it would have been four of the last five if not for the last-second empty netter on Sunday. With another tight-checking affair likely on Tuesday, the Under 5.5 is my favorite play, while a potential +200 return on the Wild is the only way I can look at the moneyline."

👉 Check out our full Wild vs. Golden Knights prediction for expert analysis, betting picks, and our favorite prop bets.

🪄 NHL playoff live betting tips for today 

Devils vs. Hurricanes Game 2 live betting tips 

• 25 of the Hurricanes' 32 home wins were by two goals or more
• In Game 1, Hurricanes improved to 20-2-0 when scoring the opener at Lenovo Center
• The Devils are 4-8-1 on the road since Jack Hughes' injury
• The Devils are 0-8-1 when allowing the first goal since Hughes' injury
• The Devils are 0-4-0 on the road when trailing after the first period since Hughes' injury
• The Hurricanes are 12-1-0 at home when leading after the first period

Senators vs. Maple Leafs Game 2 live betting tips 

• The Maple Leafs improved to 27-3-0 when leading after the first period and 35-8-2 after netting the opener
• The Senators are 1-11-3 when trailing after the first period on the road
• The Senators are 8-7-0 when outshooting the opponent on the road
• The Senators are 0-14-1 when trailing after two periods on the road
• Anthony Stolarz hasn't allowed more than two goals in seven of his previous nine starts

Panthers vs. Lightning Game 1 live betting tips 

• The Panthers are 3-8-1 on the road, scoring the fewest goals per game (1.83) since Matthew Tkachuk was sidelined
• Since Feb. 25, the Panthers are 10-4-0 when scoring the first goal
• The Lightning had the third-worst record in one-goal games during the regular season (10-9-8)
• The Panthers had the third-best record in one-goal games during the regular season (17-6-4)
• The Lightning scored the second-most goals per game on home ice during the regular season (3.90)

Wild vs. Golden Knights Game 2 live betting tips 

• The Golden Knights have won all 11 games at T-Mobile Arena that were decided by two goals
• The Golden Knights improved to 18-3-2 when scoring the first goal at home
• Adin Hill is 9-2-1 in his last 11 starts but allowed three goals five times
• Including Game 1, the Wild are 19-7-3 on the road with Kirill Kaprizov in the lineup

🔮 Tonight's expert NHL picks

• Stanley Cup odds and predictions today
• Devils vs. Hurricanes prediction
• Senators vs. Maple Leafs prediction
• Panthers vs. Lightning prediction
• Wild vs. Golden Knights prediction

🧠 Stanley Cup predictions, expert picks 

• Stanley Cup playoffs AI predictions
• Stanley Cup odds and matchups confirmed: Which teams have the advantage?
• Stats and trends to base your NHL picks and predictions on
• Best Round 1 underdog, long-shot picks
• Stanley Cup odds
• Stanley Cup odds and Round 1 injury updates
• Stanley Cup betting guide

🥅 2025 Stanley Cup Playoffs betting odds & NHL expert picks

Looking to bet on today's games? Here are some helpful tips and our picks to keep you sharp through the Stanley Cup playoffs:

• NHL odds
• NHL picks
• NHL player prop odds
• How to bet on NHL
• Stanley Cup betting guide

💵 Best hockey betting sites

Ready to place your hockey bets today? Here are the best NHL betting sites and best sportsbook promos for the Stanley Cup playoffs:

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• bet365 Bonus Code: SBRBONUS | Read our bet365 Review
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• DraftKings Promo Code | Read our DraftKings Review

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