Final Four Odds & Betting Lines: Duke, Auburn, Florida, Houston Favorites to Reach San Antonio
With conference tournaments underway and Selection Sunday nearly here, Duke and Auburn remain the most significant favorites by the Final Four odds and look set to earn No. 1 seeds in the NCAA Tournament.
Those two sit atop the March Madness odds, and a Final Four oddsboard littered with SEC and Big 12 teams. That includes Houston, Florida, Alabama, Tennessee, and Iowa State making up the other programs with odds shorter than +450 to reach San Antonio.
4️⃣ Final Four odds 2025
Final Four odds from our March Madness betting sites.
- Duke: With Wooden Award odds favorite Cooper Flagg, the Blue Devils are positioned for a one-seed, and potentially the top overall seed, and they're easily the best team in a weak ACC
- Auburn: With Johni Broome leading the way, the Tigers are projected to earn the No. 1 overall seed in the NCAA Tournament by our SBR bracketology, despite playing one of the toughest schedules in recent memory
- Houston: After an inconsistent start to the season, Houston has again solidified itself as the best team in the Big 12, and it sits third behind Auburn and Duke in the latest AP Top 25 Poll
- Florida: The Gators bounced back from their loss to Georgia to close the regular season with wins over Texas A&M and Alabama, both of which beat Auburn
- Alabama: Playing a gauntlet of a seven-game stretch to close the season, the Crimson Tide's odds lengthened following losses to Missouri, Tennessee, and Florida, but they managed to beat Auburn in OT
🍀 Final Four odds favorites 2025
😈 Duke Final Four odds (-150)
Only two teams have beaten Auburn this season, and Duke was one of them. With Flagg living up to the NBA draft odds buzz as a two-way nightmare, the Blue Devils look capable of competing with any team in the country and have a serious chance to win out and take home the ACC Tournament title with how bad the conference is this year.
While Flagg is carrying the load, this team has more than just him with fellow freshman studs Kon Knueppel and Khaman Maluach and veterans Tyrese Proctor and Sion James. I have a tough time seeing both Duke and Auburn not push to the Final Four with how much talent they both have and how much better they've both been than every other program this season. If the Blue Devils reach the Final Four a $10 bet at BetMGM pays a $6.67 profit.
Best odds: -150 via BetMGM | Implied probability: 60%
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🐯 Auburn Final Four odds (-140)
If Flagg doesn't win the Wooden, it will be Broome, who has looked as good as ever since returning from injury. While Auburn dropped games to Texas A&M and Alabama to close the regular season, they also beat Alabama and Kentucky decisively not long ago and survived one of the hardest schedules in college basketball history.
Having a good showing in the SEC Tournament will be needed for Auburn to earn the No. 1 overall seed in the NCAA Tournament over Duke, but regardless, this is a roster talented enough to reach the Final Four. If they do, a $10 bet pays a $7.14 profit at FanDuel.
Best odds: -140 via FanDuel | Implied probability: 58.33%
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🛑 Houston Final Four odds (+150)
The Cougars once again have a suffocating defense capable of taking the air out of opposing offenses. But a slow start that included losses to Auburn and Alabama has me wondering what the Cougars ceiling can be with this style, we saw them lose in the Sweet 16 last year as a No. 1 seed with their defense-first mentality.
While I like the combo of guard L.J. Cryer and forward J'Wan Roberts as a one-two punch, Houston lacks a player capable of taking over on offense in crunch time. Despite a tough stretch to close the season, Houston is set to earn a No. 1 seed. A $10 bet at DraftKings pays a $15 profit if the Cougars can reach the Final Four.
Best odds: +150 via DraftKings | Implied probability: 40%
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👀 My Final Four contender to watch
🌪️ St. John's Final Four odds (+450)
If you love defensive basketball, instead of backing Houston at +150, why not look at St. John's and what Rick Pitino is doing in the Big East? Especially with a $10 winning bet paying a $45 profit at BetRivers. The Red Storm have completely turned it around in Pitino's second season as bench boss, thanks to the play of RJ Luis, Kadary Richmond, and Zuby Ejiofor.
That trio has St. John's poised to potentially earn a top-three seed after winning the Big East regular season title, and I think they're a dark horse for a top-two seed if the SEC cannibalizes itself and the Red Storm win the Big East Tournbament. And unlike Houston, Pitino has a scorer capable of putting the team on his back when needed in Luis.
Best odds: +450 via BetRivers | Implied probability: 18.18%
🔢 Final Four odds history
Here is a look at Final Four odds history. UConn had +2000 pre-season odds last season. The year prior the Huskies had +8000 odds.
| Year | March Madness champion | Preseason Final Four odds |
|---|---|---|
| 2023-24 | UConn | +2000 |
| 2022-23 | UConn | +8000 |
| 2021-22 | Kansas | +1400 |
| 2020-21 | Baylor | +800 |
| 2018-19 | Virginia | +1350 |
| 2017-18 | Villanova | +2700 |
| 2016-17 | North Carolina | +1900 |
| 2015-16 | Villanova | +2500 |
| 2014-15 | Duke | +900 |
| 2013-14 | Connecticut | +6500 |
| 2012-13 | Louisville | +700 |
📊 What schools have the most Final Four appearances?
| School | Final Four appearances | Last appearance |
|---|---|---|
| North Carolina | 21 | 2022 |
| UCLA | 18 | 2021 |
| Duke | 17 | 2022 |
| Kentucky | 17 | 2015 |
| Kansas | 15 | 2022 |
| Michigan State | 10 | 2019 |
| Ohio State | 10 | 2012 |
| Indiana | 8 | 2002 |
| Louisville | 8 | 2013 |
| UConn | 7 | 2024 |
❓March Madness FAQs
Who is the 2025 Final Four odds favorite?
Duke is the biggest favorite to reach the Final Four in San Antonio in April. The Blue Devils' odds (-150) imply a 60% probability they'll reach the Final Four.
Where is the 2025 Final Four going to be played?
The 2025 Final Four will be played April 5 and 7 at Alamodome in San Antonio.
Who was the Final Four favorite last year?
The Huskies were the consensus betting favorites with odds as short as -455 to reach the Final Four during March Madness last year. Those odds gave the Huskies an implied probability of 81.98% of making the Final Four, according to our odds converter, before they eventually reached the semifinal and won it all.
Who was in last year's Final Four?
The UConn Huskies, Purdue Boilermakers, Alabama Crimson Tide, and NC State Wolfpack reached the Final Four of the NCAA Tournament after winning their respective regions in March Madness.
UConn and Purdue advanced to meet in the national championship game on Monday, April 8. The Huskies won that game 75-60 to secure back-to-back titles.
Where was the Final Four played last year?
The 2024 Final Four and national championship game were held at State Farm Stadium in Phoenix, Ariz.
March Madness betting odds pages
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